Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348930 | 0.82 | ADRA1D (0.50) | ADRA1AADRA1DADRA1BKDM4EALDH1A1 | |
| SCHEMBL2248079 | 0.79 | BCHE (0.44) | SRCPTGS2NCOA1NCOA3APP | |
| SCHEMBL30425863 | 0.74 | PGR (0.47) | ADRA1AADRA1DADRA1BCA9KDM4E | |
| SCHEMBL13315792 | 0.73 | CA12 (0.47) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL13315789 | 0.73 | MIF (0.56) | ADRA1AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL30425440 | 0.73 | MCL1 (0.46) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL13315799 | 0.72 | MAPT (0.58) | ADRA1AADRA1DADRA1BKDM4EALDH1A1 | |
| SCHEMBL3550061 | 0.72 | MAPT (0.60) | ADRA1AADRA1DADRA1BKDM4EALDH1A1 | |
| SCHEMBL13315784 | 0.71 | KDM4E (0.47) | SRCPTGS2APPCA12CA1 | |
| SCHEMBL13315783 | 0.71 | MEN1 (0.49) | SRCAPPCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552173-B2 | Compositions, probes, and conjugates and uses thereof | THIRD WAVE TECHNOLOGIES, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120010395-A1 | COMPOSITIONS, PROBES, AND CONJUGATES AND USES THEREOF | THIRD WAVE TECHNOLOGIES, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-8003771-B2 | Compositions, probes and conjugates and uses thereof | THIRD WAVE TECHNOLOGIES, INC. (US) | 2011-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010395-A1 | COMPOSITIONS, PROBES, AND CONJUGATES AND USES THEREOF | ALKBH1, ALK, DUT | ADRA1A 1771/4885ADRA1D 1749/4885ADRA1B 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.