Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminopyrine SCHEMBL26293 | 1.00 | ALOX15 (1.00) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL10489978 | 1.00 | ALOX15 (1.00) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL2818734 | 0.98 | ALOX15 (0.97) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL8723416 | 0.92 | ALOX15 (0.85) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL28152267 | 0.92 | ALOX15 (0.85) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL10493337 | 0.90 | ALOX15 (0.81) | ALOX15LMNACYP1A2THRBTSHR | |
| Propyphenazone SCHEMBL28086369 | 0.90 | LMNA (0.81) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL28086243 | 0.89 | ALOX15 (0.78) | ALOX15LMNACYP1A2THRBTSHR | |
| Aminopyrine SCHEMBL7042293 | 0.84 | ALOX15 (0.71) | ALOX15LMNACYP1A2THRBTSHR | |
| SCHEMBL13243351 | 0.84 | ALOX15 (0.72) | ALOX15LMNACYP1A2THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |