Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965484 | 0.81 | CA1 (0.42) | SIGMAR1CHKAEEF2K | |
| Hydrochloric Acid SCHEMBL251994 | 0.80 | CA1 (0.41) | SIGMAR1CHKAACHEEEF2K | |
| SCHEMBL1836416 | 0.76 | LMNA (0.46) | SIGMAR1LMNAPOLBMC4RDRD4 | |
| Bromide SCHEMBL15993836 | 0.71 | CHKA (0.36) | SIGMAR1LMNAPOLBCHKAEEF2K | |
| SCHEMBL28396396 | 0.71 | POLB (0.41) | SIGMAR1LMNAPOLBMC4RDRD4 | |
| SCHEMBL2228270 | 0.66 | SIGMAR1 (0.56) | SIGMAR1LMNAPOLBMC4RDRD4 | |
| Water SCHEMBL11786512 | 0.65 | EEF2K (0.62) | SIGMAR1LMNAPOLBMC4RACHE | |
| Hydrochloric Acid SCHEMBL11780574 | 0.65 | EEF2K (0.62) | SIGMAR1LMNAPOLBMC4RACHE | |
| SCHEMBL1044027 | 0.63 | SIGMAR1 (0.52) | SIGMAR1LMNAPOLBMC4RDRD4 | |
| SCHEMBL8188324 | 0.62 | SIGMAR1 (1.00) | SIGMAR1LMNAPOLBMC4RDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137608-A1 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS | SCO2, CYCS, NCLN | SIGMAR1 1390/4885LMNA 3174/4885POLB 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.