SCHEMBL1044027

SCHEMBL1044027

C1=CN(Cc2ccccc2)CN1Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 3/20 0.52
▸ F2 P00734 1/20 0.50
▸ PLG P00747 1/20 0.50
▸ ELANE P08246 1/20 0.50
▸ CTSG P08311 1/20 0.50
▸ CMA1 P23946 1/20 0.50
▸ CTRC Q99895 1/20 0.50
▸ FUCA1 P04066 2/20 0.45
▸ MC4R P32245 1/20 0.43
▸ CYP19A1 P11511 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ DRD4 P21917 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ EHMT2 Q96KQ7 1/20 0.42
▸ GSK3A P49840 1/20 0.41
▸ GSK3B P49841 1/20 0.41
▸ MGLL Q99685 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1046639 0.98 SIGMAR1 (0.50) SIGMAR1F2PLGELANECTSG
Hydrochloric Acid SCHEMBL9343069 0.98 SIGMAR1 (0.50) SIGMAR1F2PLGELANECTSG
SCHEMBL3457652 0.89 SIGMAR1 (0.43) SIGMAR1F2PLGELANECTSG
Phosphoric Acid SCHEMBL28041604 0.88 F2 (0.45) SIGMAR1F2PLGELANECTSG
Acetic Acid SCHEMBL28332665 0.88 CYP2D6 (0.49) F2PLGELANECTSGCMA1
SCHEMBL12220164 0.88 BCHE (0.47) SIGMAR1F2PLGELANECTSG
SCHEMBL2215754 0.88 LMNA (0.61) SIGMAR1KDM4EALDH1A1L3MBTL1LMNA
Pyridine SCHEMBL27430865 0.88 CYP19A1 (0.44) SIGMAR1F2PLGELANECTSG
SCHEMBL27994068 0.87 SIGMAR1 (0.45) SIGMAR1F2PLGELANECTSG
SCHEMBL5295885 0.86 MEN1 (0.44) SIGMAR1F2PLGELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010842-A Separation and purification method for cis-1, 3-dibenzylimidazole-2-ketone-4, 5-dicarboxylic acid in crude cyclic acid 浙江中贤生物科技有限公司 2026-05-12 — — CN claimed
US-12270152-B2 Dissolution of cellulose in ionic liquids TEXAS TECH UNIVERSITY SYSTEM (US) 2025-04-08 — — US claimed
US-20240262937-A1 Preparation of Chitin Nanocrystals and Nanowhiskers from Crustacean Biomass Using Ionic Liquid TEXAS TECH UNIVERSITY SYSTEM 2024-08-08 — — US claimed
WO-2023059499-A1 PREPARATION OF CHITIN NANOCRYSTALS AND NANOWHISKERS FROM CRUSTACEAN BIOMASS USING IONIC LIQUID TEXAS TECH UNIVERSITY SYSTEM (US) 2023-04-13 — — WO claimed
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 — — US claimed
CN-111334004-B High-elasticity polyester chip and preparation method thereof 扬州君禾薄膜科技有限公司 2022-04-26 — — CN claimed
US-20210079593-A1 Dissolution of Cellulose in Ionic Liquids TEXAS TECH UNIVERSITY SYSTEM 2021-03-18 — — US claimed
CN-111730243-A Water-soluble flux composition for hot air leveling 东莞市硕美电子材料科技有限公司 2020-10-02 — — CN claimed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 — — US claimed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 — — US claimed
CN-108062998-A Conductive nano carbon paste composition and preparation method thereof 深圳市源恒来实业有限公司 2018-05-22 — — CN claimed
CN-106117518-A A kind of imidazoles epoxy resin cure formula 柳州市强威锻造厂 2016-11-16 — — CN claimed
US-9072729-B2 Method for treating fibrosis and cancer with imidazolium and imidazolinium compounds AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-07-07 — — US claimed
US-20110178040-A1 METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-07-21 — — US claimed
CN-101983057-A Methods of treating fibrosis and cancer with imidazole and imidazoline compounds AGENCY SCIENCE TECH & RES 2011-03-02 — — CN claimed
US-20110028513-A1 METHOD FOR TREATING NEUROLOGICAL DISORDERS WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-02-03 — — US claimed
EP-2271338-A1 METHOD FOR TREATING NEUROLOGICAL DISORDERS WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS Agency for Science, Technology And Research (SG) 2011-01-12 — — EP claimed
EP-2249832-A1 METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS Agency for Science, Technology And Research (SG) 2010-11-17 — — EP claimed
WO-2009123569-A1 METHOD FOR TREATING NEUROLOGICAL DISORDERS WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-10-08 — — WO claimed
WO-2009096905-A1 METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-08-06 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028513-A1 METHOD FOR TREATING NEUROLOGICAL DISORDERS WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS SMN1; SMN2, INA, NLN SIGMAR1 2605/4885F2 4675/4885PLG 1657/4885
US-20110178040-A1 METHOD FOR TREATING FIBROSIS AND CANCER WITH IMIDAZOLIUM AND IMIDAZOLINIUM COMPOUNDS MMP1, MYLK, MMP8 SIGMAR1 2971/4885F2 2523/4885PLG 1680/4885
US-12270152-B2 Dissolution of cellulose in ionic liquids CEL, MGAM, SI SIGMAR1 2187/4885F2 2648/4885PLG 2879/4885
US-20210079593-A1 Dissolution of Cellulose in Ionic Liquids CEL, MGAM, SI SIGMAR1 2187/4885F2 2648/4885PLG 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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