SCHEMBL133208

SCHEMBL133208

CCCCCC(CCCOCC1CO1)[Si](OC)(OC)OC

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.58
TSHR P16473 2/20 0.47
PDK1 Q15118 1/20 0.34
MAPK1 P28482 1/20 0.33
SPHK2 Q9NRA0 1/20 0.33
SPHK1 Q9NYA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28904552 0.99 ALDH1A1 (0.62) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL27836060 0.93 SMN1; SMN2 (0.56) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL1006495 0.88 SMN1; SMN2 (0.53) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL29077312 0.84 TSHR (0.49) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL27902491 0.82 TSHR (0.44) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL27816552 0.80 SMN1; SMN2 (0.54) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL27920159 0.80 TSHR (0.44) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL6053204 0.79 TSHR (0.53) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL16424050 0.78 ALDH1A1 (0.65) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL7752331 0.78 ALDH1A1 (0.96) ALDH1A1TDP1SMN1; SMN2TSHRPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140360408-A1 ALKYD RESIN COMPOSITION COMPRISING SILICA DYRUP A/S (DK) 2014-12-11 US claimed
EP-2798015-A1 ALKYD RESIN COMPOSITION COMPRISING SILICA PERSTORP AB (SE) 2014-11-05 EP claimed
WO-2013100836-A1 ALKYD RESIN COMPOSITION COMPRISING SILICA PERSTORP AB (SE) 2013-07-04 WO claimed
US-12258516-B2 Methods to use water shutoff material composition comprising alkaline nanosilica dispersion and sodium bicarbonate in downhole conditions SAUDI ARABIAN OIL COMPANY (SA) 2025-03-25 US disclosed
US-20230183545-A1 METHODS TO USE WATER SHUTOFF MATERIAL COMPOSITION COMPRISING ALKALINE NANOSILICA DISPERSION AND SODIUM BICARBONATE IN DOWNHOLE CONDITIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-06-15 US disclosed
US-20210363402-A1 COMPOSITION AND METHOD FOR WATER AND GAS SHUT-OFF IN SUBTERRANEAN FORMATIONS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2021-11-25 US disclosed
EP-3625306-A1 COMPOSITION AND METHOD FOR WATER AND GAS SHUT-OFF IN SUBTERRANEAN FORMATIONS Saudi Arabian Oil Company (SA) 2020-03-25 EP disclosed
WO-2018213050-A1 COMPOSITION AND METHOD FOR WATER AND GAS SHUT-OFF IN SUBTERRANEAN FORMATIONS SAUDI ARABIAN OIL COMPANY (SA) 2018-11-22 WO disclosed
US-20180327648-A1 COMPOSITION AND METHOD FOR WATER AND GAS SHUT-OFF IN SUBTERRANEAN FORMATIONS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2018-11-15 US disclosed
US-9932492-B2 Alkyd resin composition comprising silica PERSTORP AB (SE) 2018-04-03 US disclosed
US-20170369734-A1 ALKYD RESIN COMPOSITION COMPRISING SILICA PERSTORP AB (SE) 2017-12-28 US disclosed
EP-1945746-B1 COMPOSITION WITH SURFACE MODIFYING PROPERTIES ECOLAB INC (US) 2010-02-10 EP disclosed
US-20100006006-A1 Water-Soluble Silicates and Use Thereof COGNIS IP MANAGEMENT GMBH (DE) 2010-01-14 US disclosed
EP-2137268-A1 COATING COMPOSITION FOR METAL SUBSTRATES Akzo Nobel Coatings International BV (NL) 2009-12-30 EP disclosed
US-20090318598-A1 Aqueous Silica-Based Nanocomposite Polymer Dispersion ARKEMA FRANCE (FR) 2009-12-24 US disclosed
WO-2009133144-A1 LAMINATE AND METHOD FOR THE PRODUCTION THEREOF BOREALIS AGROLINZ MELAMINE GMBH (AT) 2009-11-05 WO disclosed
US-20090007936-A1 Composition with Surface Modifying Properties ECOLAB USA INC. 2009-01-08 US disclosed
WO-2008128932-A1 COATING COMPOSITION FOR METAL SUBSTRATES AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2008-10-30 WO disclosed
EP-1945746-A1 COMPOSITION WITH SURFACE MODIFYING PROPERTIES ECOLAB, INC. (US) 2008-07-23 EP disclosed
WO-2007054126-A1 COMPOSITION WITH SURFACE MODIFYING PROPERTIES ECOLAB INC. (US) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100006006-A1 Water-Soluble Silicates and Use Thereof SFN, AQP3, ORAI3 ALDH1A1 4682/4885TDP1 4044/4885SMN1; SMN2 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.