Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.50 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978664 | 0.88 | ERN1 (0.50) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL5517444 | 0.84 | MEN1 (0.53) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL6214835 | 0.84 | ALDH1A1 (0.49) | ERN1ALDH1A1KDM4EHPGDESR1 | |
| SCHEMBL1654624 | 0.82 | ERN1 (0.54) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL1053945 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDESR1ESR2 | |
| SCHEMBL3958076 | 0.80 | MAPT (0.49) | ALDH1A1KDM4EHPGDPTGS1CYP3A4 | |
| SCHEMBL2051289 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDESR1ESR2 | |
| SCHEMBL3337249 | 0.79 | ERN1 (0.51) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL13321963 | 0.79 | KDM4E (0.40) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL3957273 | 0.78 | SRD5A1 (0.45) | ERN1ALDH1A1KDM4EHPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115519842-B | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-115519842-A | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-115519842-B | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115519842-B | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-115519842-A | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-115519842-A | Soft sleep-aiding quilt cover fabric and preparation method thereof | 江苏斯得福纺织股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| US-20100144729-A1 | COUMARIN DERIVATIVES | NOVARTIS AG (CH) | 2010-06-10 | — | — | US | disclosed |
| US-20090318546-A1 | Chromen-2-One Derivatives | NOVARTIS AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-2109606-A1 | CHROMENE S1P1 RECEPTOR ANTAGONIST | Novartis Ag (CH) | 2009-10-21 | — | — | EP | disclosed |
| EP-2010511-A1 | CHROMEN-2-ONE DERIVATIVES | Novartis AG (CH) | 2009-01-07 | — | — | EP | disclosed |
| WO-2008092930-A1 | CHROMENE S1P1 RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 2008-08-07 | — | — | WO | disclosed |
| WO-2007115820-A1 | CHROMEN-2-ONE DERIVATIVES | NOVARTIS AG (CH) | 2007-10-18 | — | — | WO | disclosed |
| EP-1256583-B1 | Pyrimidine-4-one derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-10 | — | — | EP | disclosed |
| US-6747032-B2 | DOUBLE ALPHA 2/5-HT 2C ANTAGONISTS USED TO TREAT DEPRESSION, IMPULSIVE BEHAVIOUR DISORDERS, ANXIETY, SCHIZOPHRENIA, PARKINSON'S DISEASE, COGNITIVE DISORDERS AND DISORDERS INVOLVING SEXUAL FUNCTION, SLEEP AND EATING | LES LABORATOIRES SERVIER (FR) | 2004-06-08 | — | — | US | disclosed |
| US-20030087916-A1 | Pyrimidin-4-one compounds | LES LABORATOIRES SERVIER (FR) | 2003-05-08 | — | — | US | disclosed |
| EP-1256583-A1 | Pyrimidine-4-one derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | CYP1A2, CYP4B1, CYP1B1 | ERN1 1633/4885TLR2 3287/4885TLR1 3515/4885 |
| US-20100144729-A1 | COUMARIN DERIVATIVES | F3, CYP3A7, CYP3A4 | ERN1 908/4885TLR2 2753/4885TLR1 3070/4885 |
| US-20030087916-A1 | Pyrimidin-4-one compounds | HTR2C, HTR1A, HTR4 | ERN1 2675/4885TLR2 541/4885TLR1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.