Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13321973 | 0.93 | LMNA (0.59) | KMT2ALMNAMAPTMAPK1CYP1A2 | |
| SCHEMBL17263307 | 0.88 | TUBB4A (0.64) | KMT2ALMNAMAPTMAPK1MEN1 | |
| SCHEMBL11911278 | 0.84 | LMNA (0.66) | KMT2ALMNAMAPTRAB9AHPGD | |
| SCHEMBL13321977 | 0.84 | KMT2A (0.50) | KMT2ALMNAMAPTMAPK1MEN1 | |
| SCHEMBL13321974 | 0.83 | KMT2A (0.49) | KMT2ALMNAMAPTMAPK1MEN1 | |
| SCHEMBL9963642 | 0.82 | MAPT (0.68) | KMT2ALMNAMAPTMAPK1MEN1 | |
| SCHEMBL14430924 | 0.82 | KMT2A (0.57) | KMT2ALMNAMAPTMEN1CYP1A2 | |
| SCHEMBL10022910 | 0.82 | KMT2A (0.56) | KMT2ALMNAMAPTMAPK1MEN1 | |
| SCHEMBL14407753 | 0.81 | LMNA (0.66) | KMT2ALMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL13503146 | 0.81 | LMNA (0.66) | KMT2ALMNAMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436118-B2 | Synthesis of acylarylenes and hyperbranched poly(aclarylene)s by metal-free cyclotrimerization of alkynes | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-05-07 | — | — | US | disclosed |
| US-20100129757-A1 | SYNTHESIS OF ACYLARYLENES AND HYPERBRANCHED POLY(ACLARYLENE)S BY METAL-FREE CYCLOTRIMERIZATION OF ALKYNES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-05-27 | — | — | US | disclosed |