Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13321973 | 0.91 | LMNA (0.59) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12762432 | 0.90 | GAA (0.49) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12762430 | 0.89 | LMNA (0.59) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12762443 | 0.85 | MAPT (0.54) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13321975 | 0.84 | KMT2A (0.56) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5451478 | 0.82 | HPGD (0.73) | KMT2ALMNAHPGDL3MBTL1PTGIR | |
| SCHEMBL13321974 | 0.81 | KMT2A (0.49) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11295113 | 0.80 | LMNA (0.55) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10022910 | 0.80 | KMT2A (0.56) | KMT2ALMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11911278 | 0.79 | LMNA (0.66) | KMT2ALMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436118-B2 | Synthesis of acylarylenes and hyperbranched poly(aclarylene)s by metal-free cyclotrimerization of alkynes | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-05-07 | — | — | US | disclosed |
| US-20100129757-A1 | SYNTHESIS OF ACYLARYLENES AND HYPERBRANCHED POLY(ACLARYLENE)S BY METAL-FREE CYCLOTRIMERIZATION OF ALKYNES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-05-27 | — | — | US | disclosed |