Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936626 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BADAMTS4LOXL2KDM4E | |
| SCHEMBL16656704 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1BADAMTS4LOXL2PYGL | |
| Acetic Acid SCHEMBL5533726 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BADAMTS4LOXL2KDM4E | |
| SCHEMBL25885232 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BADAMTS4LOXL2PYGL | |
| SCHEMBL5159413 | 0.75 | ADAMTS4 (0.54) | MTNR1AMTNR1BADAMTS4LOXL2PYGL | |
| SCHEMBL5365001 | 0.73 | LOXL2 (0.55) | MTNR1AMTNR1BADAMTS4LOXL2 | |
| SCHEMBL5249054 | 0.73 | LOXL2 (0.55) | MTNR1AMTNR1BADAMTS4LOXL2 | |
| SCHEMBL3120573 | 0.73 | MTNR1A (0.60) | MTNR1AMTNR1BLOXL2KDM4EALDH1A1 | |
| SCHEMBL30305027 | 0.73 | LOXL2 (0.55) | MTNR1AMTNR1BADAMTS4LOXL2 | |
| SCHEMBL9027554 | 0.73 | LOXL2 (0.58) | MTNR1AMTNR1BLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709484-B1 | Substituted melanocortin receptor-specific piperazine compounds | PALATIN TECHNOLOGIES, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| US-7709484-B1 | Substituted melanocortin receptor-specific piperazine compounds | PALATIN TECHNOLOGIES, INC. (US) | 2010-05-04 | — | — | US | disclosed |