Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | WRN | Q14191 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365539 | 0.81 | GSK3A (0.49) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL5163732 | 0.79 | GSK3A (0.66) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL1103799 | 0.77 | GSK3A (0.52) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL877582 | 0.74 | CA12 (0.58) | ALDH1A1LMNAMAPTNPSR1PKM | |
| SCHEMBL1103791 | 0.74 | GSK3A (0.48) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL12291174 | 0.72 | GSK3A (0.52) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL18101913 | 0.72 | GSK3A (0.47) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL11955666 | 0.72 | GSK3A (0.55) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL437306 | 0.71 | GSK3A (0.50) | GSK3AGSK3BALDH1A1BLMHPGD | |
| SCHEMBL29995038 | 0.70 | GSK3A (0.48) | GSK3AGSK3BALDH1A1BLMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113643-A1 | CURATIVES FOR EPOXY ADHESIVE COMPOSITIONS | DESIGNER MOLECULES, INC. (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113643-A1 | CURATIVES FOR EPOXY ADHESIVE COMPOSITIONS | ALOX5, LTC4S, ALOX15B | GSK3A 4857/4885GSK3B 4874/4885ALDH1A1 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.