Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PRNP | P04156 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325643 | 0.85 | FGFR1 (0.46) | ALDH1A1KDM4ELMNASMN1; SMN2PRNP | |
| SCHEMBL13325646 | 0.81 | DCTPP1 (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2IDO1 | |
| SCHEMBL9908306 | 0.78 | DHODH (0.39) | ALDH1A1KDM4ELMNASMN1; SMN2PRNP | |
| SCHEMBL13325639 | 0.76 | IDO1 (0.48) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL13325635 | 0.76 | IDO1 (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2GFER | |
| SCHEMBL11530601 | 0.75 | CYP1A2 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL13325755 | 0.73 | HPGD (0.39) | LMNASMN1; SMN2HPGDHSD17B10KCNN4 | |
| SCHEMBL30001203 | 0.73 | LMNA (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2PRNP | |
| SCHEMBL31268510 | 0.73 | MPO (0.60) | ALDH1A1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL435000 | 0.69 | HTT (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709655-B2 | Clickphosphines for transition metal-catalyzed reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | WEE1, WEE2, ITK | ALDH1A1 2744/4885KDM4E 1779/4885LMNA 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.