SCHEMBL435000

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12530335	0.83	L3MBTL1 (0.48)	HTTTP53SMN1; SMN2MEN1KMT2A
	SCHEMBL12530453	0.80	ALDH1A1 (0.56)	TP53SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL10091953	0.79	NOTUM (0.62)	HTTSMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL28209542	0.79	TP53 (0.53)	HTTTP53SMN1; SMN2MEN1KMT2A
	SCHEMBL2891386	0.79	HTT (0.56)	HTTTP53SMN1; SMN2ALOX12MEN1
	SCHEMBL12758937	0.79	HTT (0.61)	HTTTP53SMN1; SMN2ALOX12MEN1
	SCHEMBL12530467	0.79	PTGS2 (0.60)	HTTTP53SMN1; SMN2MEN1KMT2A
	SCHEMBL12530492	0.79	GRM1 (0.56)	ALDH1A1L3MBTL1
	SCHEMBL13325667	0.78	NPC1 (0.62)	HTTTP53SMN1; SMN2ALOX12MEN1
	SCHEMBL2891435	0.78	HTT (0.54)	HTTTP53SMN1; SMN2ALOX12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.