Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325640 | 0.85 | ALDH1A1 (0.48) | FGFR1SMN1; SMN2TSHRALDH1A1KDM4E | |
| SCHEMBL13325762 | 0.78 | FGFR1 (0.40) | FGFR1SMN1; SMN2TSHRALDH1A1NPC1 | |
| SCHEMBL11530601 | 0.75 | CYP1A2 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL13325953 | 0.73 | FGFR1 (0.36) | FGFR1SMN1; SMN2MAP4K1SLC2A1SLC2A2 | |
| SCHEMBL13325646 | 0.71 | DCTPP1 (0.51) | SMN1; SMN2TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL13325652 | 0.71 | HSD11B1 (0.40) | SMN1; SMN2TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL13325639 | 0.70 | IDO1 (0.48) | ALDH1A1KDM4EMAPTHIF1AHPGD | |
| SCHEMBL435000 | 0.69 | HTT (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL9908306 | 0.67 | DHODH (0.39) | FGFR1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL13325650 | 0.67 | ALDH1A1 (0.50) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709655-B2 | Clickphosphines for transition metal-catalyzed reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | WEE1, WEE2, ITK | FGFR1 2924/4885SMN1; SMN2 2910/4885TSHR 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.