Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916120 | 0.74 | NPC1 (0.50) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL28985365 | 0.70 | SIGMAR1 (0.48) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL28446478 | 0.70 | KDM4E (0.52) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL29462500 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL4386835 | 0.70 | ALDH1A1 (0.56) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL13425127 | 0.69 | HCAR1 (0.47) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL27659049 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL2188830 | 0.68 | CYP11B1 (0.48) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL11478440 | 0.67 | SMN1; SMN2 (0.56) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL28215247 | 0.67 | NPC1 (0.42) | ALDH1A1MAPTHSD17B10HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709655-B2 | Clickphosphines for transition metal-catalyzed reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088166-A1 | Clickphosphines for transition metal-catalyzed reactions | WEE1, WEE2, ITK | ALDH1A1 2744/4885MAPT 4057/4885HSD17B10 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.