Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331865 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL6113736 | 0.97 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL8771797 | 0.88 | MAPT (0.54) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL8771609 | 0.88 | MAPT (0.54) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL16775458 | 0.88 | MAPT (0.54) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL1333625 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL1333623 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL20805873 | 0.85 | MAPT (0.55) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL12125154 | 0.85 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTHDAC3HDAC11 | |
| SCHEMBL8771773 | 0.84 | MAPT (0.57) | ALDH1A1LMNAMAPTHDAC3HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | claimed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | claimed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | claimed |
| EP-2970760-B1 | PHOTOCHROMIC ARTICLES THAT INCLUDE PHOTOCHROMIC-DICHROIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2019-06-26 | — | — | EP | claimed |
| US-10145996-B2 | Photochromic articles that include photochromic-dichroic materials | TRANSITIONS OPTICAL, INC. (US) | 2018-12-04 | — | — | US | claimed |
| EP-3268375-A1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | Transitions Optical, Inc. (US) | 2018-01-17 | — | — | EP | claimed |
| EP-3071576-A1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | Transitions Optical, Inc. (US) | 2016-09-28 | — | — | EP | claimed |
| EP-3071551-A1 | FUSED RING INDENO COMPOUNDS FOR PREPARATION OF PHOTOCHROMIC COMPOUNDS | Transitions Optical, Inc. (US) | 2016-09-28 | — | — | EP | claimed |
| WO-2016144324-A1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2016-09-15 | — | — | WO | claimed |
| US-20160209561-A1 | Photochromic Articles That Include Photochromic-Dichroic Materials | TRANSITIONS OPTICAL, INC. | 2016-07-21 | — | — | US | claimed |
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | claimed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | claimed |
| US-9051332-B1 | Photochromic indeno-fused ring pyran compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-06-09 | — | — | US | claimed |
| WO-2015077141-A1 | FUSED RING INDENO COMPOUNDS FOR PREPARATION OF PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | claimed |
| WO-2015077264-A1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | claimed |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-21 | — | — | US | claimed |
| US-9029565-B1 | Fused ring indeno compounds for preparation of photochromic compounds | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | claimed |
| US-20140272468-A1 | PHOTOCHROMIC ARTICLES THAT INCLUDE PHOTOCHROMIC-DICHROIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2014-09-18 | — | — | US | claimed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | claimed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | ALDH1A1 1243/4885LMNA 657/4885MAPT 573/4885 |
| US-20150141661-A1 | Photochromic Indeno-Fused Ring Pyran Compounds | INF2, INCENP, RB1 | ALDH1A1 654/4885LMNA 263/4885MAPT 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.