SCHEMBL1332964

SCHEMBL1332964

CC#Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLG P54098 2/20 0.51
POLB P06746 3/20 0.51
P2RY2 P41231 3/20 0.50
P2RY4 P51582 2/20 0.50
P2RY6 Q15077 2/20 0.50
DTYMK P23919 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3471801 0.91 TYMS (0.52) POLB
SCHEMBL8417572 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL10022245 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL5664015 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL22327108 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL5664002 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL8417580 0.91 POLG (0.51) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL25492015 0.90 POLG (0.50) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL25492103 0.90 POLG (0.50) POLGPOLBP2RY2P2RY4P2RY6
SCHEMBL22189180 0.90 POLG (0.53) POLGPOLBP2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240344109-A1 METHODS OF DETERMINING THE NUMBER OF COPIES OR SEQUENCE OF ONE OR MORE RNA MOLECULES BASIC GENOMICS AB (SE) 2024-10-17 US claimed
EP-4381093-A1 METHODS OF DETERMINING THE NUMBER OF COPIES OR SEQUENCE OF ONE OR MORE RNA MOLECULES Basic Genomics AB (SE) 2024-06-12 EP claimed
CN-117813393-A Method for determining copy number or sequence of one or more RNA molecules 基础基因组学公司 2024-04-02 CN claimed
WO-2023012065-A1 METHODS OF DETERMINING THE NUMBER OF COPIES OR SEQUENCE OF ONE OR MORE RNA MOLECULES BASIC GENOMICS AB (SE) 2023-02-09 WO claimed
US-20190100784-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac SE (DE) 2019-04-04 US claimed
EP-3423595-A1 RNA ANALYSIS BY TOTAL HYDROLYSIS CureVac AG (DE) 2019-01-09 EP claimed
US-20160289679-A1 NUCLEIC ACID LIGANDS TO LL37 BIOTEX INC (US) 2016-10-06 US claimed
US-20150259688-A1 NUCLEIC ACID LIGANDS TO LL37 BIOTEX INC (US) 2015-09-17 US claimed
US-9044495-B2 Nucleic acid ligands to LL37 BIOTEX, INC. (US) 2015-06-02 US claimed
US-20120121533-A1 NUCLEIC ACID LIGANDS TO LL37 BIOTEX, INC. (US) 2012-05-17 US claimed
EP-4747380-A1 MODULATING EXPRESSION OF ALAS1 (5'-AMINOLEVULINATE SYNTHASE 1) GENE CRISPR Therapeutics AG (CH) 2026-05-27 EP disclosed
US-20260137769-A1 NUCLEIC ACID MOLECULES AND USES THEREOF CureVac SE (DE) 2026-05-21 US disclosed
US-20260137768-A1 ZIKA VIRUS VACCINE CureVac SE (DE) 2026-05-21 US disclosed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 CN disclosed
CN-122070365-A Systems and compositions comprising highly active trans-amplified replicase 百欧恩泰欧洲股份公司 2026-05-19 CN disclosed
US-9044495-B2 Nucleic acid ligands to LL37 BIOTEX, INC. (US) 2015-06-02 US disclosed
WO-2015062738-A1 MODIFIED RNA WITH DECREASED IMMUNOSTIMULATORY PROPERTIES CUREVAC GMBH (DE) 2015-05-07 WO disclosed
US-8212020-B2 Reagents for reversibly terminating primer extension BENNER STEVEN ALBERT (US) 2012-07-03 US disclosed
US-20120121533-A1 NUCLEIC ACID LIGANDS TO LL37 BIOTEX, INC. (US) 2012-05-17 US disclosed
US-20110275124-A1 Reagents for reversibly terminating primer extension BENNER STEVEN A 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275124-A1 Reagents for reversibly terminating primer extension RNGTT, POLRMT, DNTT POLG 89/4885POLB 28/4885P2RY2 1132/4885
US-20260137768-A1 ZIKA VIRUS VACCINE ADAR, RNGTT, UPF1 POLG 3051/4885POLB 1949/4885P2RY2 1015/4885
US-20260137769-A1 NUCLEIC ACID MOLECULES AND USES THEREOF RNMT, RNGTT, NSUN3 POLG 1112/4885POLB 733/4885P2RY2 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.