Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330652 | 0.93 | ALDH1A1 (0.58) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL13020034 | 0.83 | TDP1 (0.63) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL16204069 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL14923033 | 0.79 | KDM4E (0.64) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL13330658 | 0.79 | NQO2 (0.57) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL6758121 | 0.78 | DHFR (0.47) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL18562426 | 0.75 | MEN1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL17358402 | 0.75 | BCHE (0.56) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL14211983 | 0.74 | KDM4E (0.45) | ALDH1A1KDM4EL3MBTL1MAPTLMNA | |
| SCHEMBL16543285 | 0.74 | KDM4E (0.45) | ALDH1A1KDM4EL3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353065-B2 | Heterocyclic bridged biphenyls | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| US-20100109514-A1 | HETEROCYCLIC BRIDGED BIPHENYLS | UDC IRELAND LIMITED (IE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100109514-A1 | HETEROCYCLIC BRIDGED BIPHENYLS | OCIAD1, SBDS, OCIAD2 | ALDH1A1 358/4885KDM4E 3206/4885L3MBTL1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.