SCHEMBL6758121

SCHEMBL6758121

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.47
PIK3CG P48736 1/20 0.47
ADORA2A P29274 3/20 0.47
NUDT1 P36639 3/20 0.47
LMNA P02545 3/20 0.46
HTT P42858 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TP53 P04637 1/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 4/20 0.45
GAA P10253 4/20 0.45
HPGD P15428 3/20 0.45
ALPL P05186 1/20 0.45
IDO1 P14902 1/20 0.45
TTK P33981 1/20 0.45
MAPK10 P53779 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14211983 0.95 KDM4E (0.45) DHFRPIK3CGADORA2ANUDT1LMNA
SCHEMBL16543285 0.95 KDM4E (0.45) DHFRPIK3CGADORA2ANUDT1LMNA
SCHEMBL13020034 0.88 TDP1 (0.63) ADORA2ALMNAHTTMEN1KMT2A
SCHEMBL13293090 0.86 DHFR (0.44) DHFRPIK3CGADORA2ANUDT1LMNA
SCHEMBL23474671 0.85 KDM4E (0.57) ADORA2ANUDT1LMNAHTTMEN1
SCHEMBL12722989 0.85 GPR3 (0.45) ADORA2ANUDT1LMNAMEN1KMT2A
SCHEMBL13197741 0.84 LMNA (0.54) DHFRPIK3CGADORA2ALMNAHTT
SCHEMBL4750622 0.83 ADK (0.40) DHFRPIK3CGADORA2ANUDT1LMNA
SCHEMBL2403323 0.83 IDO1 (0.47) LMNAHTTMEN1KMT2ATP53
SCHEMBL20921183 0.82 L3MBTL1 (0.48) DHFRPIK3CGADORA2ANUDT1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030138662-A1 Organic light-emitting devices CANON KABUSHIKI KAISHA (JP) 2003-07-24 US claimed
WO-2003058667-A1 ORGANIC LIGHT-EMITTING DEVICES CANON KABUSHIKI KAISHA (JP) 2003-07-17 WO claimed
US-6723445-B2 Organic light-emitting devices CANON KABUSHIKI KAISHA (JP) 2004-04-20 US disclosed
US-20030138662-A1 Organic light-emitting devices CANON KABUSHIKI KAISHA (JP) 2003-07-24 US disclosed
WO-2003058667-A1 ORGANIC LIGHT-EMITTING DEVICES CANON KABUSHIKI KAISHA (JP) 2003-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138662-A1 Organic light-emitting devices DDX18, RECQL, DDX1 DHFR 1397/4885PIK3CG 3929/4885ADORA2A 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.