Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022661 | 0.81 | ACHE (0.58) | MEN1KMT2AHSD17B10ALDH1A1HBB | |
| SCHEMBL1855652 | 0.81 | ACHE (0.58) | MEN1KMT2AHSD17B10ALDH1A1HBB | |
| SCHEMBL4221590 | 0.81 | ACHE (0.58) | MEN1KMT2AHSD17B10ALDH1A1HBB | |
| SCHEMBL12237554 | 0.81 | ADORA3 (0.41) | S100A4HSD17B10ALDH1A1HBBMAPT | |
| SCHEMBL66876 | 0.74 | ACHE (0.64) | S100A4MEN1KMT2APOLBHSD17B10 | |
| SCHEMBL5952358 | 0.72 | ACHE (0.40) | S100A4HSD17B10ALDH1A1HBBMAPT | |
| SCHEMBL5952731 | 0.72 | ACHE (0.41) | POLBHSD17B10ALDH1A1HBBMAPT | |
| SCHEMBL8845683 | 0.72 | PIM1 (0.41) | HSD17B10ALDH1A1HBBACHECYP19A1 | |
| SCHEMBL4459322 | 0.71 | S100A4 (0.61) | S100A4MEN1KMT2APOLBHSD17B10 | |
| SCHEMBL16377312 | 0.71 | S100A4 (0.55) | S100A4MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871916-B2 | Diaryl phosphine compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-08-08 | — | — | US | disclosed |
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | disclosed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | TREH, TALDO1, LIPE | S100A4 4746/4885MEN1 345/4885KMT2A 1865/4885 |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | TREH, TALDO1, LIPE | S100A4 4746/4885MEN1 345/4885KMT2A 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.