Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25983036 | 0.95 | KIF11 (0.52) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL13525482 | 0.89 | KIF11 (0.44) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL29837993 | 0.86 | KIF11 (0.45) | KIF11RXRARXRGXDHTAS2R14 | |
| SCHEMBL628008 | 0.86 | KIF11 (0.45) | KIF11RXRARXRGXDHTAS2R14 | |
| SCHEMBL23133402 | 0.84 | KIF11 (0.44) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL16952575 | 0.84 | KIF11 (0.44) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL1336331 | 0.84 | RXRA (0.45) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL11954934 | 0.84 | KIF11 (0.44) | KIF11RXRARXRGCES2XDH | |
| SCHEMBL628010 | 0.84 | KIF11 (0.44) | KIF11RXRARXRGXDHTAS2R14 | |
| SCHEMBL14169297 | 0.84 | KIF11 (0.44) | KIF11RXRARXRGCES2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514773-B | Verdinexor (KPT-335) and synthesis method of hydrochloride thereof | 重庆汉佩生物科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-116514773-A | Verdinexor (KPT-335) and synthesis method of hydrochloride thereof | 重庆汉佩生物科技有限公司 | 2023-08-01 | — | — | CN | claimed |
| US-11318120-B2 | Nuclear transport modulators and uses thereof | BIOGEN MA INC. (US) | 2022-05-03 | — | — | US | claimed |
| US-20210251968-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | BIOGEN MA INC. (US) | 2021-08-19 | — | — | US | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| CN-1795177-A | 1, 2, 4-substituted 1, 2, 3, 4-tetrahydro-and 1, 2 dihydro-quinolines and 1, 2, 3, 4-tetrahydro-quinoxaline derivatives as CETP inhibitors for the treatment of atherosclerosis and obesity | PFIZER PROD INC (US) | 2006-06-28 | — | — | CN | claimed |
| US-20040110990-A1 | Catalytic reduction of nitriles to aldehydes | LANXESS DEUTSCHLAND GMBH (DE) | 2004-06-10 | — | — | US | claimed |
| EP-1389608-A1 | Catalytic reduction of benzonitrile derivatives to benzoaldehyde derivatives | Bayer Chemicals AG (DE) | 2004-02-18 | — | — | EP | claimed |
| US-6362372-B2 | HYDROGENATION OF A TRIFLUOROBENZYLNITRILE BY HYDROGEN IN AN ORGANIC SOLVENT IN THE PRESENCE OF AMMONIA AND A CATALYST COMPRISING A PLATINUM GROUP ELEMENT; EXTREMELY HIGH YIELDS | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-03-26 | — | — | US | claimed |
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | claimed |
| US-6242623-B1 | POLYMERIZATION CATALYSTS OF COORDINATION CATALYSTS | SYMYX TECHNOLOGIES, INC. | 2001-06-05 | — | — | US | claimed |
| US-4822903-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-04-18 | — | — | US | claimed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | claimed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | claimed |
| CN-122091739-A | Dynamic response type electrolyte and preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-122059977-A | Near infrared emission asymmetric BODIPY fluorescent material and preparation method thereof | 华南理工大学 | 2026-05-19 | — | — | CN | disclosed |
| US-20260062391-A1 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | disclosed |
| US-3962257-A | 3-PHENACYLPIPERIDINES | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | IDH1, INMT, TH | KIF11 2157/4885RXRA 4272/4885RXRG 4330/4885 |
| US-20210251968-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | XPO1, XPO5, XPOT | KIF11 1257/4885RXRA 312/4885RXRG 273/4885 |
| US-11318120-B2 | Nuclear transport modulators and uses thereof | XPO1, XPO5, XPOT | KIF11 1257/4885RXRA 312/4885RXRG 273/4885 |
| US-20260062391-A1 | HYDRAZIDE CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | SLC8A1, SLC9A1, SLC8B1 | KIF11 1161/4885RXRA 2532/4885RXRG 2614/4885 |
| US-20040110990-A1 | Catalytic reduction of nitriles to aldehydes | CAT, NIT2, IDH1 | KIF11 4751/4885RXRA 4160/4885RXRG 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.