Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312488 | 0.92 | PTGER4 (0.44) | PTGER4PTGER2AVPR1AMEN1KMT2A | |
| SCHEMBL13312492 | 0.80 | PTGER4 (0.53) | PTGER4PTGER2RAB9ASMN1; SMN2POLB | |
| SCHEMBL13312462 | 0.80 | FFAR1 (0.46) | PTGER4PTGER2NPC1RAB9A | |
| SCHEMBL13312484 | 0.79 | PTGER4 (0.45) | PTGER4PTGER2 | |
| SCHEMBL13312490 | 0.78 | PTGER4 (0.45) | PTGER4PTGER2AVPR1ANPC1RAB9A | |
| SCHEMBL13312491 | 0.78 | FFAR1 (0.46) | PTGER4PTGER2 | |
| SCHEMBL13312482 | 0.76 | FFAR1 (0.47) | PTGER4PTGER2MEN1KMT2ATP53 | |
| SCHEMBL13312479 | 0.76 | FFAR1 (0.44) | PTGER4PTGER2MEN1KMT2AALDH1A1 | |
| SCHEMBL13312477 | 0.76 | PTGER2 (0.51) | PTGER4PTGER2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13348291 | 0.76 | PTGER2 (0.60) | PTGER4PTGER2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER4 1432/4885PTGER2 3346/4885AVPR1A 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.