Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 6/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312496 | 0.92 | PTGER4 (0.61) | PTGER2PTGER4RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL13312502 | 0.82 | FFAR1 (0.49) | PTGER2PTGER4FFAR1 | |
| SCHEMBL13312434 | 0.79 | FFAR1 (0.48) | PTGER2PTGER4FFAR1 | |
| SCHEMBL13312477 | 0.78 | PTGER2 (0.51) | PTGER2PTGER4SMN1; SMN2FFAR1ALDH1A1 | |
| SCHEMBL13348170 | 0.78 | PTGER4 (0.39) | PTGER2PTGER4RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13312501 | 0.78 | PTGER4 (0.46) | PTGER2PTGER4RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL13312440 | 0.78 | FFAR1 (0.44) | PTGER2PTGER4FFAR1 | |
| SCHEMBL13312452 | 0.78 | FFAR1 (0.45) | PTGER2PTGER4FFAR1 | |
| SCHEMBL13348240 | 0.77 | PTGER2 (0.49) | PTGER2PTGER4RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13312504 | 0.77 | FFAR1 (0.48) | PTGER2PTGER4RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER2 3346/4885PTGER4 1432/4885RAB9A 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.