SCHEMBL133482

SCHEMBL133482

O=C(c1ccccc1)c1ccc(-c2cc(-c3ccc(C(=O)c4ccccc4)cc3)cc(-c3ccc(C(=O)c4ccccc4)cc3)c2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
MAPT P10636 2/20 0.72
LMNA P02545 1/20 0.72
ALDH1A1 P00352 1/20 0.67
ATM Q13315 2/20 0.62
SRD5A2 P31213 2/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA9 Q16790 2/20 0.60
CA12 O43570 1/20 0.60
CA14 Q9ULX7 1/20 0.60
EGFR P00533 1/20 0.59
CDC25B P30305 1/20 0.55
POLB P06746 1/20 0.55
MAPK1 P28482 1/20 0.55
NPC1 O15118 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14449092 0.94 ATM (0.75) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL197633 0.93 RAB9A (0.82) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL13019488 0.93 RAB9A (0.82) RAB9AMEN1KMT2AMAPTLMNA
Benzophenone SCHEMBL28231198 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
Benzene SCHEMBL28384085 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL41657 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL28246134 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL13534566 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL29143580 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA
Benzophenone SCHEMBL15567912 0.90 RAB9A (0.78) RAB9AMEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225503-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-08-16 EP claimed
WO-2022073742-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2022-04-14 WO claimed
US-20220106488-A1 Grinding Aid for Titanium Dioxide Particles KRONOS INTERNATIONAL INC. (DE) 2022-04-07 US claimed
US-7153891-B2 Photoinitiator blends for high speed triggering CRYOVAC, INC. (US) 2006-12-26 US claimed
WO-2005066300-A1 PHOTOINITIATOR BLENDS FOR HIGH SPEED TRIGGERING CRYOVAC, INC. (US) 2005-07-21 WO claimed
US-20050148680-A1 Photoinitiator blends for high speed triggering CRYOVAC, INC. 2005-07-07 US claimed
US-20230416535-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-12-28 US disclosed
EP-4225503-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-08-16 EP disclosed
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
WO-2022073742-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2022-04-14 WO disclosed
US-20220106488-A1 Grinding Aid for Titanium Dioxide Particles KRONOS INTERNATIONAL INC. (DE) 2022-04-07 US disclosed
US-20220089848-A1 Oxygen Scavenging Composition TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2022-03-24 US disclosed
US-20050287318-A1 Method of removing sulfur odors from packages CRYOVAC, INC. 2005-12-29 US disclosed
WO-2005107502-A1 OXYGEN SCAVENGING FILM WITH CYCLIC OLEFIN COPOLYMER CRYOVAC, INC. (US) 2005-11-17 WO disclosed
US-20050244665-A1 Oxygen scavenging film with cyclic olefin copolymer CRYOVAC, INC. 2005-11-03 US disclosed
WO-2005066300-A1 PHOTOINITIATOR BLENDS FOR HIGH SPEED TRIGGERING CRYOVAC, INC. (US) 2005-07-21 WO disclosed
WO-2005066300-A1 PHOTOINITIATOR BLENDS FOR HIGH SPEED TRIGGERING CRYOVAC, INC. (US) 2005-07-21 WO disclosed
US-20050148680-A1 Photoinitiator blends for high speed triggering CRYOVAC, INC. 2005-07-07 US disclosed
US-20050148680-A1 Photoinitiator blends for high speed triggering CRYOVAC, INC. 2005-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 RAB9A 1959/4885MEN1 402/4885KMT2A 3489/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 RAB9A 2000/4885MEN1 2301/4885KMT2A 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.