SCHEMBL1334847

SCHEMBL1334847

CCCCCC=CCC=CCC=CC/C=C\CCCCCC(=O)NCCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 7/20 1.00
▸ ALDH1A1 P00352 3/20 1.00
▸ HPGD P15428 2/20 1.00
▸ TRPV1 Q8NER1 2/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ BLM P54132 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ MAPT P10636 1/20 1.00
▸ ALOX12 P18054 1/20 1.00
▸ TDP1 Q9NUW8 1/20 1.00
▸ TRPM8 Q7Z2W7 1/20 0.91
▸ FAAH O00519 1/20 0.91
▸ KCNK3 O14649 1/20 0.91
▸ CNR2 P34972 1/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Linoleoylethanolamide SCHEMBL653623 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL30306296 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL6259736 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL14106445 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL14864036 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
Linoleoylethanolamide SCHEMBL5145794 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL5412597 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL14106447 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL17097089 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1
Linoleoylethanolamide SCHEMBL13110450 1.00 CNR1 (1.00) CNR1ALDH1A1HPGDTRPV1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294411-A4 A NOVEL TREATMENT FOR COUGH UNIV CALIFORNIA (US) 2006-02-01 — — EP claimed
US-6974568-B2 Treatment for cough THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-13 — — US claimed
EP-1294411-A1 A NOVEL TREATMENT FOR COUGH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-03-26 — — EP claimed
US-20020035150-A1 Novel treatment for cough REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2002-03-21 — — US claimed
WO-2001089589-A1 A NOVEL TREATMENT FOR COUGH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-29 — — WO claimed
EP-0670826-B1 FATTY ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RES DEV CO (IL) 2000-04-26 — — EP claimed
US-5618955-A ANTIINFLAMMATORY AGENTS, ANALGESICS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1997-04-08 — — US claimed
EP-0670826-A4 FATTY ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. YISSUM RES DEV CO (IL) 1996-08-14 — — EP claimed
JP-H08504195-A — — 1996-05-07 — — JP claimed
EP-0670826-A1 FATTY ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1995-09-13 — — EP claimed
WO-1994012466-A1 FATTY ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1994-06-09 — — WO claimed
US-20110280807-A1 Methods and Models for Stress-Induced Analgesia UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2011-11-17 — — US disclosed
US-20090082435-A1 Methods, Compositions, And Compounds For Modulation Of Monoacylglycerol Lipase, Pain, And Stress-Related Disorders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-03-26 — — US disclosed
US-20080103209-A1 Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-05-01 — — US disclosed
WO-2006116703-A2 METHODS AND MODELS FOR STRESS-INDUCED ANALGESIA UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2006-11-02 — — WO disclosed
US-6974568-B2 Treatment for cough THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-13 — — US disclosed
EP-1294411-A1 A NOVEL TREATMENT FOR COUGH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-03-26 — — EP disclosed
US-20020035150-A1 Novel treatment for cough REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2002-03-21 — — US disclosed
WO-2001089589-A1 A NOVEL TREATMENT FOR COUGH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-11-29 — — WO disclosed
EP-0670826-B1 FATTY ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YISSUM RES DEV CO (IL) 2000-04-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103209-A1 Compounds And Methods For Treating Non-Inflammatory Pain Using Ppar Alpha Agonists FAAH, CNR2, FAAH2 CNR1 4/4885ALDH1A1 967/4885HPGD 187/4885
US-20090082435-A1 Methods, Compositions, And Compounds For Modulation Of Monoacylglycerol Lipase, Pain, And Stress-Related Disorders MGLL, PNLIP, LIPC CNR1 273/4885ALDH1A1 1248/4885HPGD 358/4885
US-20020035150-A1 Novel treatment for cough CNR1, CNR2, TRPV1 CNR1 1/4885ALDH1A1 3682/4885HPGD 2184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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