Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13767210 | 0.77 | USP8 (0.35) | APOBEC3AAPOBEC3GMAPTMEN1ALDH1A1 | |
| SCHEMBL11143567 | 0.77 | CYP2D6 (0.44) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11933957 | 0.77 | CYP1B1 (0.44) | APOBEC3AAPOBEC3GMAPTMEN1ALDH1A1 | |
| SCHEMBL13266801 | 0.76 | OPRD1 (0.42) | APOBEC3AAPOBEC3GMAPTMEN1ALDH1A1 | |
| SCHEMBL13848549 | 0.73 | HTT (0.35) | APOBEC3AAPOBEC3GMAPTMEN1ALDH1A1 | |
| SCHEMBL14095369 | 0.73 | ALDH1A1 (0.42) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL12878065 | 0.73 | MPI (0.46) | APOBEC3AAPOBEC3GMAPTALDH1A1KDM4E | |
| SCHEMBL30892213 | 0.73 | CA12 (0.56) | APOBEC3GMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL12463621 | 0.73 | CA12 (0.56) | APOBEC3GMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6209642 | 0.73 | KDM4E (0.41) | MAPTMEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | PFKP, PDXK, PF4 | APOBEC3A 4591/4885APOBEC3G 4609/4885MAPT 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.