SCHEMBL1335295

SCHEMBL1335295

Cc1ccc(-c2n[nH]cc2C=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
DUSP3 P51452 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
NPC1 O15118 3/20 0.41
ALDH1A1 P00352 4/20 0.38
CYP2A6 P11509 1/20 0.38
ERBB2 P04626 1/20 0.38
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
DCUN1D1 Q96GG9 1/20 0.35
NOTUM Q6P988 1/20 0.35
KDM4E B2RXH2 3/20 0.35
POLB P06746 1/20 0.35
PTK2B Q14289 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336717 0.83 CDK4 (0.49) RAB9ASMN1; SMN2KMT2AMEN1NPC1
SCHEMBL4908543 0.82 ESR1 (0.41) RAB9ASMN1; SMN2KMT2AMEN1NPC1
SCHEMBL1335905 0.82 XDH (0.39) RAB9ASMN1; SMN2L3MBTL1NPC1ALDH1A1
SCHEMBL4246815 0.82 PTGS2 (0.47) RAB9ASMN1; SMN2KMT2AMEN1NPC1
SCHEMBL1335198 0.81 PTGS2 (0.45) RAB9ASMN1; SMN2KMT2AMEN1NPC1
SCHEMBL28220671 0.80 NOTUM (0.41) RAB9ASMN1; SMN2NPC1ALDH1A1MAPT
SCHEMBL17670183 0.80 KMT2A (0.43) SMN1; SMN2KMT2AMEN1ALDH1A1MAPK1
SCHEMBL16201312 0.79 ALDH1A3 (0.49) KMT2AMAPK1MAPTNOTUM
SCHEMBL3006649 0.78 NOTUM (0.40) RAB9ANPC1MAPK1NOTUMKDM4E
SCHEMBL13592411 0.78 NOTUM (0.40) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
WO-2025125829-A1 NORA INHIBITORS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-06-19 WO disclosed
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP disclosed
US-9475831-B2 Formylpyrrole-based heterocycles for nucleic acid attachment to supports ILLUMINA, INC. (US) 2016-10-25 US disclosed
US-20160137677-A1 FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS ILLUMINA, INC. 2016-05-19 US disclosed
US-9273074-B2 Formylpyrrole-based heterocycles for nucleic acid attachment to supports ILLUMINA, INC. (US) 2016-03-01 US disclosed
EP-2748295-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2015-10-14 EP disclosed
US-20150031833-A1 FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS ILLUMINA, INC. 2015-01-29 US disclosed
WO-2011149995-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2011-12-01 WO disclosed
US-20110281870-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS ABBOTT LABORATORIES (US) 2011-11-17 US disclosed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN disclosed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP disclosed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO disclosed
US-20090093464-A1 Naphthalene Derivatives as Modulators of the Glucocorticoid Receptor SMITHKLINE BEECHMA CORPORATION (US) 2009-04-09 US disclosed
EP-1851204-A1 NAPHTHALENE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR SmithKline Beecham Corporation (US) 2007-11-07 EP disclosed
WO-2006091592-A1 NAPHTHALENE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR SMITHKLINE BEECHAM CORPORATION (US) 2006-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031833-A1 FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS CCNY, FBL, NSUN2 RAB9A 4620/4885SMN1; SMN2 2481/4885DUSP3 4074/4885
US-20160137677-A1 FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS CCNY, FBL, NSUN2 RAB9A 4620/4885SMN1; SMN2 2481/4885DUSP3 4074/4885
US-20110281870-A1 NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS CACNA1C, ORAI1, CACNA1S RAB9A 2076/4885SMN1; SMN2 1139/4885DUSP3 4702/4885
US-20090093464-A1 Naphthalene Derivatives as Modulators of the Glucocorticoid Receptor NR3C1, NR3C2, NR5A1 RAB9A 4357/4885SMN1; SMN2 4723/4885DUSP3 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.