Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335295 | 0.83 | RAB9A (0.44) | KMT2AMEN1ALDH1A1CYP2A6KDM4E | |
| SCHEMBL16201312 | 0.83 | ALDH1A3 (0.49) | CDK4CDK2KMT2AERN1MAPT | |
| Hydrochloric Acid SCHEMBL16194267 | 0.81 | ALDH1A3 (0.47) | CDK4CDK2KMT2AERN1MAPT | |
| SCHEMBL16223030 | 0.80 | LMNA (0.56) | ERN1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL4246815 | 0.79 | PTGS2 (0.47) | CDK4CDK2KMT2AMEN1ERN1 | |
| SCHEMBL4908543 | 0.79 | ESR1 (0.41) | KMT2AMEN1ERN1MAPTNPC1 | |
| SCHEMBL1335905 | 0.79 | XDH (0.39) | ERN1ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL1335198 | 0.79 | PTGS2 (0.45) | KMT2AMEN1NLRP3ALDH1A1CYP2A6 | |
| SCHEMBL22607800 | 0.78 | ERN1 (0.54) | ERN1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4244705 | 0.78 | ALDH1A1 (0.41) | CDK4CDK2KMT2AMEN1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125829-A1 | NORA INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| CN-119367357-A | Use of PSPH inhibitor in preparation of medicine for preventing, treating or improving nervous system diseases | 中国医学科学院基础医学研究所 | 2025-01-28 | — | — | CN | disclosed |
| CN-113968819-B | Synthesis method of polysubstituted pyrazole compound | 成都普康唯新生物科技有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-113968819-A | Synthesis method of polysubstituted pyrazole compound | 成都普赛唯新生物科技有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-9475831-B2 | Formylpyrrole-based heterocycles for nucleic acid attachment to supports | ILLUMINA, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20160137677-A1 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS | ILLUMINA, INC. | 2016-05-19 | — | — | US | disclosed |
| US-9273074-B2 | Formylpyrrole-based heterocycles for nucleic acid attachment to supports | ILLUMINA, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150031833-A1 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS | ILLUMINA, INC. | 2015-01-29 | — | — | US | disclosed |
| US-8883764-B1 | Formylpyrrole-based heterocycles for nucleic acid attachment to supports | ILLUMINA, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| WO-2011149995-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110281870-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2011-11-17 | — | — | US | disclosed |
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
| US-7067534-B1 | Substituted anilinic piperidines as MCH selective antagonists | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| CN-1671386-A | Substituted anilinic piperidines as MCH selective antagonists | LUNDBECK & CO AS H (DK) | 2005-09-21 | — | — | CN | disclosed |
| EP-1301517-B1 | THIENOPYRROLIDINONES | HOFFMANN LA ROCHE (CH) | 2004-12-15 | — | — | EP | disclosed |
| US-6727264-B1 | MELANIN CONCENTRATING HORMONE-1 RECEPTOR ANTAGONISTS; SLEEP, EATING, SEXUAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-27 | — | — | US | disclosed |
| EP-1301517-A1 | THIENOPYRROLIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-16 | — | — | EP | disclosed |
| US-6528653-B2 | E.g., 4,6-dihydro 4-(heterocyclic ring-methylene)thieno(2,3-b) pyrrolidin-5-one derivatives; tumor necrosis factor ) inhibitors; anticarcinogenic, -proliferative and -arthritic agents; Alzheimer's disease; cardiovascular disorders | HOFFMANN-LA ROCHE, INC. | 2003-03-04 | — | — | US | disclosed |
| US-20020028841-A1 | Thienopyrrolidinones | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | US | disclosed |
| WO-2002002567-A1 | THIENOPYRROLIDINONES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | CDK4 3729/4885CDK2 3739/4885KMT2A 1037/4885 |
| US-20150031833-A1 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS | CCNY, FBL, NSUN2 | CDK4 417/4885CDK2 910/4885KMT2A 2474/4885 |
| US-20160137677-A1 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS | CCNY, FBL, NSUN2 | CDK4 417/4885CDK2 910/4885KMT2A 2474/4885 |
| US-20110281870-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA[C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | CACNA1C, ORAI1, CACNA1S | CDK4 943/4885CDK2 633/4885KMT2A 3363/4885 |
| US-20020028841-A1 | Thienopyrrolidinones | TNF, TYMP, TNFRSF1A | CDK4 72/4885CDK2 84/4885KMT2A 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.