Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | ACACA | Q13085 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloeucalenol SCHEMBL569261 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| Cycloeucalenol SCHEMBL569260 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| Cycloeucalenol SCHEMBL13801858 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL31672688 | 0.85 | EBP (0.51) | HSD11B1ACLYACACAPTPN11ESR2 | |
| SCHEMBL31672687 | 0.84 | ACLY (0.61) | HSD11B1ACLYACACAPTPN11ESR2 | |
| SCHEMBL1878721 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL14520017 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL14047057 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL12152345 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL982765 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709666-B2 | Transgenic plants containing altered levels of sterol compounds and tocopherols | MONSANTO TECHNOLOGY LLC (US) | 2010-05-04 | — | — | US | disclosed |