Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | ACACA | Q13085 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloeucalenol SCHEMBL569260 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| Cycloeucalenol SCHEMBL13358786 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| Cycloeucalenol SCHEMBL13801858 | 1.00 | HSD11B1 (0.54) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL31672688 | 0.85 | EBP (0.51) | HSD11B1ACLYACACAPTPN11ESR2 | |
| SCHEMBL31672687 | 0.84 | ACLY (0.61) | HSD11B1ACLYACACAPTPN11ESR2 | |
| SCHEMBL1878721 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL14520017 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL14047057 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL12152345 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 | |
| SCHEMBL982765 | 0.84 | ACLY (0.63) | HSD11B1PTPN1ACLYACACAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111690591-B | Diuretic active drug cell screening model and establishment method and application thereof | 贵州中医药大学 | 2022-03-15 | — | — | CN | claimed |
| CN-111690591-A | Diuretic active drug cell screening model and establishment method and application thereof | 贵州中医药大学 | 2020-09-22 | — | — | CN | claimed |
| EP-2470647-B1 | GENETICALLY MODIFIED ORGANISMS FOR THE PRODUCTION OF LIPIDS | NOVOZYMES AS (DK) | 2017-04-19 | — | — | EP | claimed |
| US-9598710-B2 | Genetically modified organism for the production of lipids | ORGANOBALANCE GMBH (DE) | 2017-03-21 | — | — | US | claimed |
| CN-102812124-B | Genetically engineered organisms for lipid production | ORGANOBALANCE GMBH (DE) | 2016-05-18 | — | — | CN | claimed |
| US-20150024009-A1 | GENETICALLY MODIFIED ORGANISM FOR THE PRODUCTION OF LIPIDS | ORGANOBALANCE GMBH (DE) | 2015-01-22 | — | — | US | claimed |
| US-8841114-B2 | Genetically modified organism for the production of lipids | ORGANOBALANCE GMBH (DE) | 2014-09-23 | — | — | US | claimed |
| EP-2586859-A1 | Genetically modified organisms for the production of lipids | OrganoBalance GmbH (DE) | 2013-05-01 | — | — | EP | claimed |
| CN-102812124-A | Genetically engineered organisms for lipid production | ORGANOBALANCE GMBH | 2012-12-05 | — | — | CN | claimed |
| CN-101570560-B | Two sterol derivatives, separation and extraction method thereof and application thereof in preventing and treating prostatoplasia diseases | SHANGHAI INST PHARM INDUSTRY | 2012-07-11 | — | — | CN | claimed |
| US-20030195367-A1 | Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry | LABORATOIRES EXPANSCIENCE (FR) | 2003-10-16 | — | — | US | claimed |
| EP-1301460-A1 | METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY | Laboratoires Expanscience (FR) | 2003-04-16 | — | — | EP | claimed |
| US-20020148006-A1 | Transgenic plants with modified sterol compositions | ASGROW SEED COMPANY, L.L.C. | 2002-10-10 | — | — | US | claimed |
| WO-2002006205-B1 | METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY | PHARMASCIENCE LAB (FR) | 2002-03-21 | — | — | WO | claimed |
| WO-2002006205-A1 | METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY | LABORATOIRES EXPANSCIENCE (FR) | 2002-01-24 | — | — | WO | claimed |
| EP-0958370-A1 | TRANSGENIC PLANTS WITH MODIFIED STEROL BIOSYNTHETIC PATHWAYS | MONSANTO COMPANY (US) | 1999-11-24 | — | — | EP | claimed |
| WO-1998045457-A1 | TRANSGENIC PLANTS WITH MODIFIED STEROL BIOSYNTHETIC PATHWAYS | MONSANTO COMPANY (US) | 1998-10-15 | — | — | WO | claimed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| CN-85109752-A | Preparation triterpenoid organic acid ester and the method that contains the hypolipidemic agents of this compounds | — | 1986-12-17 | — | — | CN | claimed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195367-A1 | Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry | LSS, CYP51A1, CYP46A1 | HSD11B1 8/4885PTPN1 2796/4885ACLY 2551/4885 |
| US-20020148006-A1 | Transgenic plants with modified sterol compositions | SREBF1, SREBF2, ERG28 | HSD11B1 117/4885PTPN1 4288/4885ACLY 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.