Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ITGAM | P11215 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26845482 | 0.92 | KMT2A (0.41) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL26845477 | 0.89 | KMT2A (0.42) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL13124538 | 0.89 | MEN1 (0.37) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL26845349 | 0.84 | ADRB2 (0.38) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL26845333 | 0.84 | INSR (0.40) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL13107781 | 0.82 | NPC1 (0.49) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL26845399 | 0.82 | KMT2A (0.37) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL26845364 | 0.81 | NPC1 (0.37) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL13359353 | 0.81 | PRMT1 (0.41) | KMT2AMEN1HTTBLMNPC1 | |
| SCHEMBL13124705 | 0.81 | NPC1 (0.34) | KMT2AMEN1HTTBLMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709653-B2 | Asymmetric cyanine compounds, their preparation methods and their uses | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO. LTD. (CN) | 2010-05-04 | — | — | US | disclosed |
| US-20090305285-A1 | ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES | SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090305285-A1 | ASYMMETRIC CYANINE COMPOUNDS, THEIR PREPARATION METHODS AND THEIR USES | IK, RCN1, RCC1 | KMT2A 1677/4885MEN1 2874/4885HTT 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.