SCHEMBL1335946

SCHEMBL1335946

Brc1ccccc1Nc1ccccc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.54
ADRA2A P08913 1/20 0.54
ADRA2C P18825 1/20 0.54
ADRA1D P25100 1/20 0.54
ADRA1A P35348 1/20 0.54
ADRA1B P35368 1/20 0.54
MAPT P10636 1/20 0.54
CXCR2 P25025 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
HTT P42858 2/20 0.45
MEN1 O00255 1/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.44
TSHR P16473 1/20 0.43
C1R P00736 1/20 0.43
LRRK2 Q5S007 1/20 0.42
FABP4 P15090 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21185968 0.85 MAPT (0.56) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL13800817 0.85 ADRA2A (0.44) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL13800739 0.85 ALDH1A1 (0.54) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL29414646 0.85 MAPT (0.56) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL3270611 0.84 MAPT (0.56) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL31425489 0.84 MAPT (0.56) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL17968621 0.82 ALDH1A1 (0.58) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL20829121 0.82 ALDH1A1 (0.59) ALDH1A1MAPTMEN1RAB9AKMT2A
SCHEMBL20605197 0.81 L3MBTL1 (0.50) ALDH1A1ADRA2AADRA2CADRA1DADRA1A
SCHEMBL4124208 0.80 MAPT (0.56) ALDH1A1MAPTL3MBTL1HTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118904263-A Preparation device and preparation method of phenothiazine 湖北普瑞提化工科技有限公司 2024-11-08 CN claimed
CN-117777052-A Preparation method of phenothiazine 郑州海阔光电材料有限公司 2024-03-29 CN claimed
CN-113603715-A Preparation method of 10, 10-diphenylsilaacridine 黑龙江省科学院石油化学研究院 2021-11-05 CN claimed
CN-107325037-B Preparation method of 1-bromocarbazole 北京八亿时空液晶科技股份有限公司 2020-03-13 CN claimed
WO-2018217538-A1 SYNTHESIS OF SUBSTITUTED ACRIDINES UNIVERSITY OF ST. THOMAS (US) 2018-11-29 WO claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
CN-117777052-B Preparation method of phenothiazine 郑州海阔光电材料有限公司 2025-09-19 CN disclosed
US-20250160196-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO. LTD. (KR) 2025-05-15 US disclosed
US-20250122227-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNITED STATES DEPARTMENT OF ENERGY 2025-04-17 US disclosed
US-12256633-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-03-18 US disclosed
CN-119613445-A Organic compound containing germanium, excitation compound containing germanium and application of excitation compound 深圳大学 2025-03-14 CN disclosed
CN-111217858-B Organometallic compound and organic light emitting device including the same 三星显示有限公司 2025-02-25 CN disclosed
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
US-6284699-B1 COORDINATION POLYMERIZATION CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-04 US disclosed
EP-1114832-A1 Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-11 EP disclosed
US-20010007007-A1 Modified particles, catalyst for olefin polymerization using the same, and process of producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-05 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
EP-0949273-A1 MODIFIED PARTICLES, CARRIER PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST COMPONENT PREPARED THEREFROM, OLEFIN POLYMERIZATION CATALYST PREPARED THEREFROM, AND PROCESS FOR PREPARING OLEFIN POLYMER Sumitomo Chemical Company, Limited (JP) 1999-10-13 EP disclosed
US-4898802-A Toner compositions with organo boron negative charge enhancing additives XEROX CORPORATION (US) 1990-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 ALDH1A1 737/4885ADRA2A 3854/4885ADRA2C 4030/4885
US-20250160196-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, ODC1, LEF1 ALDH1A1 96/4885ADRA2A 4099/4885ADRA2C 4451/4885
US-20250122227-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC ALDH1A1 318/4885ADRA2A 2697/4885ADRA2C 2075/4885
US-12256633-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device PIEZO1, ODC1, LEF1 ALDH1A1 96/4885ADRA2A 4099/4885ADRA2C 4451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.