Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350463 | 0.76 | AKR1C3 (0.61) | AKR1C3AKR1C2DGAT1 | |
| SCHEMBL8924164 | 0.72 | LMNA (0.45) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL27301550 | 0.72 | SLC6A4 (0.44) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL17574540 | 0.72 | SLC6A4 (0.44) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL20096396 | 0.71 | DGAT1 (0.41) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL1747848 | 0.71 | CASP6 (0.33) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL1747849 | 0.71 | CASP6 (0.33) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL12844795 | 0.71 | AKR1C3 (0.44) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL27702411 | 0.71 | DGAT1 (0.40) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL15797527 | 0.70 | AKR1C3 (0.40) | AKR1C3AKR1C2CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572656-B1 | COMPOUNDS USEFUL AS PESTICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-26 | — | — | EP | disclosed |