Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18431523 | 0.86 | NR1I2 (0.41) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL27023470 | 0.82 | DGAT1 (0.40) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL12891661 | 0.82 | DGAT1 (0.40) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL21618531 | 0.81 | MAPT (0.39) | DGAT1MAPTCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL8924164 | 0.80 | LMNA (0.45) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL27301550 | 0.80 | SLC6A4 (0.44) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL22746830 | 0.80 | CYP2D6 (0.40) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL17574540 | 0.80 | SLC6A4 (0.44) | DGAT1MAPTAKR1C3AKR1C2CYP2D6 | |
| SCHEMBL18737505 | 0.78 | NR1I2 (0.41) | DGAT1MAPTCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL9264510 | 0.78 | TBXAS1 (0.41) | AKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292394-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-21 | — | — | US | disclosed |
| US-20180110225-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180110225-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, DDC | DGAT1 461/4885MAPT 3379/4885AKR1C3 995/4885 |
| US-10292394-B2 | Herbicidal compounds | DDT, HPD, DDC | DGAT1 461/4885MAPT 3379/4885AKR1C3 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.