Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000039 | 0.93 | LMNA (0.58) | LMNASMN1; SMN2FLT3KDRCSNK2A1 | |
| SCHEMBL8752140 | 0.91 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL9564018 | 0.89 | LMNA (0.63) | LMNASMN1; SMN2FLT3KDRCSNK2A1 | |
| Hydrochloric Acid SCHEMBL8089018 | 0.89 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL8508 | 0.87 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL7615048 | 0.87 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL1197801 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL8509 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL3974126 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| Diatrizoic Acid SCHEMBL30451079 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113756-A1 | LUMINESCENT METAL COMPLEXES FOR MONITORING RENAL FUNCTION | REN, GLS, ATP6V1B1 | LMNA 2098/4885SMN1; SMN2 3608/4885TSHR 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.