Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054396 | 0.98 | TLR8 (0.55) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL570984 | 0.94 | TLR8 (0.54) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL27870558 | 0.83 | TLR8 (0.68) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28793625 | 0.83 | TLR8 (0.68) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28743898 | 0.81 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL286920 | 0.81 | TLR8 (0.54) | TLR8TRPV1KCNH2 | |
| SCHEMBL287399 | 0.81 | TLR8 (0.61) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL168398 | 0.81 | TLR8 (0.69) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2514453 | 0.81 | TLR8 (0.56) | TLR8ALDH1A1HPGDGLAMAPT | |
| SCHEMBL1122100 | 0.81 | RXFP1 (0.49) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134797-B1 | BIOCIDAL/HYDROPHOBIC INNER COATING OF CONDENSER PIPES (OF INDUSTRIAL TURBINES AND SUBSIDIARY COOLING CYCLES) | SIEMENS AG (DE) | 2014-06-18 | — | — | EP | claimed |
| CN-105974044-B | The method of N- acyl-homoserine lactone types of populations induction signal molecule in test sample | 清华大学深圳研究生院 | 2018-12-25 | — | — | CN | disclosed |
| CN-107667288-A | Spectral analysis of microorganisms | 英国质谱公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-105974044-A | Method for detecting N-acyl-homoserine lactone quorum sensing signal molecules in sample | 清华大学深圳研究生院 | 2016-09-28 | — | — | CN | disclosed |
| CN-101679802-B | Biocidal/hydrophobic inner coating of condenser pipes (of industrial turbines and subsidiary cooling cycles) | SIEMENS AG | 2013-09-18 | — | — | CN | disclosed |
| US-20130011400-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. (GB) | 2013-01-10 | — | — | US | disclosed |
| EP-1730197-B1 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| US-20110027280-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. (GB) | 2011-02-03 | — | — | US | disclosed |
| EP-2261260-A2 | Methods for inducing autolysis in infectious bacteria | Haptogen Ltd (GB) | 2010-12-15 | — | — | EP | disclosed |
| CN-101679802-A | Biocidal/hydrophobic inner coating of condenser pipes (of industrial turbines and subsidiary cooling cycles) | SIEMENS AG | 2010-03-24 | — | — | CN | disclosed |
| US-20100068457-A1 | BIOCIDAL/HYDROPHOBIC INNER COATING OF CONDENSER PIPES (OF INDUSTRIAL TURBINES AND SUBSIDIARY COOLING CYCLES) | SIEMENS AKTIENGESELLSCHAFT (DE) | 2010-03-18 | — | — | US | disclosed |
| US-7651699-B2 | novel way of controlling the dynamics of the rumen flora using the very compounds the natural microbial population produce themselves in feed | PATHWAY INTERMEDIATES LIMITED (GB) | 2010-01-26 | — | — | US | disclosed |
| US-20070218058-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. POLWARTH BUILDING (GB) | 2007-09-20 | — | — | US | disclosed |
| EP-1361801-B1 | AUTOINDUCER COMPOUNDS AND THEIR USES | PATHWAY INTERMEDIATES LTD (GB) | 2007-06-06 | — | — | EP | disclosed |
| EP-1730197-A2 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | Haptogen Ltd (GB) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005094883-A2 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2005-10-13 | — | — | WO | disclosed |
| US-20040115245-A1 | Autoinducer compounds and their uses | GORMAR MARKETING LIMITED (KY) | 2004-06-17 | — | — | US | disclosed |
| EP-1361801-A1 | AUTOINDUCER COMPOUNDS AND THEIR USES | Gormar Marketing Limited (KY) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002052949-A1 | AUTOINDUCER COMPOUNDS AND THEIR USES | GORMAR MARKETING LIMITED (KY) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011400-A1 | Methods For Inducing Autolysis In Infectious Bacteria | CFTR, ENPP2, BAD | TLR8 57/4885KDM4E 4823/4885ALDH1A1 4798/4885 |
| US-20110027280-A1 | Methods For Inducing Autolysis In Infectious Bacteria | CFTR, ENPP2, BAD | TLR8 57/4885KDM4E 4823/4885ALDH1A1 4798/4885 |
| US-20070218058-A1 | Methods For Inducing Autolysis In Infectious Bacteria | CFTR, BAD, ENPP2 | TLR8 38/4885KDM4E 4846/4885ALDH1A1 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.