Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260213 | 0.88 | TDP1 (0.52) | TLR8TDP1PDE10AALDH1A1GLA | |
| SCHEMBL168398 | 0.83 | TLR8 (0.69) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL14137811 | 0.82 | TLR8 (0.41) | TLR8ACHE | |
| SCHEMBL28278237 | 0.82 | TLR8 (0.55) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL2054396 | 0.82 | TLR8 (0.55) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL9714713 | 0.82 | TLR8 (0.55) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL28793625 | 0.82 | TLR8 (0.68) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL27870558 | 0.82 | TLR8 (0.68) | TLR8ALDH1A1GLAMAPTHPGD | |
| SCHEMBL17713567 | 0.82 | TLR8 (0.63) | TLR8 | |
| SCHEMBL286920 | 0.81 | TLR8 (0.54) | TLR8TDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371819-B1 | NEW QUINOLINE DERIVATIVES, A METHOD FOR THE PRODUCTION AND THE USE THEREOF FOR TREATING MICROBACTERIAL INFECTIONS AND A PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES | AKTSIONERNOE OBSCHESTVO PHARM-SINTEZ (RU) | 2018-01-10 | — | — | EP | claimed |
| EP-2371819-A1 | NEW QUINOLINE DERIVATIVES, A METHOD FOR THE PRODUCTION AND THE USE THEREOF FOR TREATING MICROBACTERIAL INFECTIONS AND A PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES | Zakrytoe Aktsionernoe Obschestvo "Pharm-Sintez" (RU) | 2011-10-05 | — | — | EP | claimed |
| EP-2371819-B1 | NEW QUINOLINE DERIVATIVES, A METHOD FOR THE PRODUCTION AND THE USE THEREOF FOR TREATING MICROBACTERIAL INFECTIONS AND A PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES | AKTSIONERNOE OBSCHESTVO PHARM-SINTEZ (RU) | 2018-01-10 | — | — | EP | disclosed |
| EP-2371819-A1 | NEW QUINOLINE DERIVATIVES, A METHOD FOR THE PRODUCTION AND THE USE THEREOF FOR TREATING MICROBACTERIAL INFECTIONS AND A PHARMACEUTICAL COMPOSITION BASED ON SAID DERIVATIVES | Zakrytoe Aktsionernoe Obschestvo "Pharm-Sintez" (RU) | 2011-10-05 | — | — | EP | disclosed |