Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133672 | 0.98 | TLR8 (0.54) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL570984 | 0.95 | TLR8 (0.54) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL168398 | 0.82 | TLR8 (0.69) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL2514453 | 0.82 | TLR8 (0.56) | TLR8ALDH1A1HPGDGLAMAPT | |
| SCHEMBL1326148 | 0.81 | TLR8 (0.60) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL17179261 | 0.81 | ALDH1A1 (0.58) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28793625 | 0.81 | TLR8 (0.68) | TLR8KDM4EALDH1A1GAAHPGD | |
| SCHEMBL9714713 | 0.81 | TLR8 (0.55) | TLR8ALDH1A1HPGDGLAMAPT | |
| SCHEMBL17713567 | 0.81 | TLR8 (0.63) | TLR8 | |
| SCHEMBL28278237 | 0.81 | TLR8 (0.55) | TLR8ALDH1A1HPGDGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9820967-B2 | Methods and compositions for increasing antibiotic activity | WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) | 2017-11-21 | — | — | US | disclosed |
| US-20160015686-A1 | Methods and Compositions for Increasing Antibiotic Activity | WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) | 2016-01-21 | — | — | US | disclosed |
| US-9074129-B2 | Mechanochromic luminescent difluoroboron beta-diketonates | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130210053-A1 | MECHANOCHROMIC LUMINESCENT DIFLUOROBORON BETA-DIKETONATES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2011068537-A2 | MECHANOCHROMIC LUMINESCENT DIFLUOROBORON BETA-DIKETONATES | FRASER CASSANDRA L (US) | 2011-06-09 | — | — | WO | disclosed |
| US-6224863-B1 | BACTERICIDE | UNIVERSITY OF SOUTH CAROLINA | 2001-05-01 | — | — | US | disclosed |