SCHEMBL13367407

SCHEMBL13367407

Cc1cccc(N(C)c2cc(C)cc(C)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.55
CSF1R P07333 5/20 0.46
EGFR P00533 4/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
SIGMAR1 Q99720 1/20 0.43
TSHR P16473 1/20 0.43
MAPT P10636 1/20 0.42
HSD17B1 P14061 2/20 0.41
HSD17B2 P37059 2/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
NSD2 O96028 1/20 0.40
CASP3 P42574 1/20 0.40
KMT2A Q03164 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697445 0.93 ACHE (0.55) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL2742923 0.86 ACHE (0.48) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL10042839 0.84 TSHR (0.46) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL5604652 0.84 TSPO (0.46) ACHEEGFRSMN1; SMN2TSHRNPC1
SCHEMBL30595088 0.84 ACHE (0.46) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL3663067 0.84 ACHE (0.46) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL20733331 0.83 ACHE (0.55) ACHECSF1REGFRMAPTHSD17B1
SCHEMBL22337431 0.83 CSF1R (0.47) ACHECSF1REGFRSMN1; SMN2SIGMAR1
SCHEMBL13509012 0.83 TSHR (0.42) ACHETSHRTDP1ALDH1A1MAPK1
SCHEMBL13241962 0.82 CHKA (0.43) CSF1REGFRHSD17B1HSD17B2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11342506-B2 Organic electroluminescent element KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-05-24 US disclosed
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-07-02 US disclosed
WO-2020054676-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 学校法人関西学院 2020-03-19 WO disclosed
WO-2020045681-A1 ORGANIC ELECTROLUMINESCENT ELEMENT USING LIGHT EMITTING MATERIAL COMPOSED OF POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-03-05 WO disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus TYR, AOC2, AOC1 ACHE 969/4885CSF1R 4216/4885EGFR 1389/4885
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS TYR, AOC2, AOC1 ACHE 969/4885CSF1R 4216/4885EGFR 1389/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 ACHE 2234/4885CSF1R 2428/4885EGFR 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.