SCHEMBL1337136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1966629	0.92	PTGES (0.56)	PTGESNPC1RAB9AL3MBTL1PRSS12
	SCHEMBL1965291	0.92	PTGES (0.56)	PTGESNPC1RAB9AL3MBTL1PRSS12
	SCHEMBL1967513	0.88	PTGES (0.58)	PTGESHDAC6SMYD3POLB
	SCHEMBL13392968	0.85	PTGES (0.55)	PTGESNPC1RAB9AL3MBTL1PRSS12
	SCHEMBL1968187	0.85	HDAC6 (0.43)	PTGESNPC1RAB9AHDAC6SMYD3
	SCHEMBL12132139	0.84	PTGES (0.55)	PTGESNPC1RAB9ARIPK1MAPK14
	SCHEMBL1251024	0.83	DGAT1 (0.62)	NPC1RAB9AL3MBTL1PRSS12MAPK14
	SCHEMBL13392979	0.83	PTGES (0.59)	PTGESNPC1RAB9AMAPK14KMT2A
	SCHEMBL1965467	0.82	POLB (0.60)	LMNAHDAC6USP2POLBESR2
	SCHEMBL1338148	0.82	PTGES (0.57)	PTGESNPC1RAB9AMAPK14CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.