Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373997 | 0.85 | NPC1 (0.40) | MAPTRAB9ANPC1GAAKDM4E | |
| SCHEMBL12903035 | 0.80 | MAPT (0.55) | MAPTRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL13373996 | 0.80 | DHFR (0.35) | MAPTRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL13373998 | 0.77 | MAPT (0.46) | MAPTRAB9ANPC1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4079309 | 0.76 | TAAR1 (0.44) | MAPTGAAKDM4ETAAR1ALDH1A1 | |
| SCHEMBL5952426 | 0.73 | ALDH1A1 (0.59) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL20433967 | 0.71 | LMNA (0.39) | MAPTGAASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13180237 | 0.71 | KMT2A (0.50) | MAPTRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL3003760 | 0.71 | MAPT (0.57) | MAPTGAAKDM4ETAAR1ALDH1A1 | |
| SCHEMBL24021272 | 0.70 | ALDH1A1 (0.49) | TAAR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |