Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | GJB2 | P29033 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381069 | 0.94 | TNF (0.35) | NT5ELMNAPTPN1PTPN2CDC25B | |
| SCHEMBL13381070 | 0.94 | NT5E (0.33) | NT5ELMNAPTPN1PTPN2CDC25B | |
| SCHEMBL13381067 | 0.88 | GJB2 (0.43) | NT5ELMNAPTPN1PTPN2CDC25B | |
| SCHEMBL13381052 | 0.88 | LMNA (0.45) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL13381065 | 0.87 | LGALS8 (0.39) | NT5ELMNAPTPN1PTPN2GJB2 | |
| SCHEMBL13381053 | 0.84 | LMNA (0.38) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL13381058 | 0.82 | LMNA (0.41) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL13381060 | 0.81 | PTPN1 (0.47) | NT5EPTPN1PTPN2CDC25BGJB2 | |
| SCHEMBL13381081 | 0.75 | PTPN1 (0.38) | LMNAPTPN1PTPN2CDC25BGJB2 | |
| SCHEMBL13381063 | 0.74 | PTPN1 (0.48) | NT5EPTPN1PTPN2CDC25BGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081708-A1 | ANTICOAGULANT COMPOUNDS | ENDOTIS PHARMA (FR) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081708-A1 | ANTICOAGULANT COMPOUNDS | SERPINC1, F2, FUT5 | NT5E 395/4885LMNA 2211/4885PTPN1 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.