Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | USP9X | Q93008 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381728 | 0.90 | CHRM3 (0.46) | KMT2AMEN1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2840994 | 0.85 | TP53 (0.58) | KMT2ATP53MEN1LMNAMAPT | |
| SCHEMBL2846313 | 0.80 | ADRB3 (0.47) | KMT2AMEN1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL2840117 | 0.80 | TP53 (0.48) | TP53LMNA | |
| SCHEMBL2838360 | 0.79 | TP53 (0.47) | TP53LMNA | |
| SCHEMBL2837650 | 0.78 | TP53 (0.57) | TP53LMNAMAPT | |
| SCHEMBL2841679 | 0.78 | ALDH1A1 (0.56) | TP53LMNA | |
| SCHEMBL2841104 | 0.77 | TP53 (0.47) | KMT2ATP53LMNA | |
| SCHEMBL2844651 | 0.76 | MEN1 (0.41) | KMT2ATP53MEN1LMNAMAPT | |
| SCHEMBL2841776 | 0.74 | LMNA (0.52) | TP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |