Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381741 | 0.85 | MMP2 (0.42) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL2837650 | 0.84 | TP53 (0.57) | TP53LMNAMAPT | |
| SCHEMBL2841104 | 0.81 | TP53 (0.47) | KMT2ATP53LMNA | |
| SCHEMBL2846313 | 0.79 | ADRB3 (0.47) | MEN1KMT2AALDH1A1MAPTPKM | |
| SCHEMBL2840117 | 0.79 | TP53 (0.48) | TP53LMNAALDH1A1 | |
| SCHEMBL2841776 | 0.79 | LMNA (0.52) | TP53LMNAHTTALDH1A1 | |
| SCHEMBL2838360 | 0.78 | TP53 (0.47) | TP53LMNAALDH1A1 | |
| SCHEMBL2840994 | 0.78 | TP53 (0.58) | MEN1KMT2ATP53LMNAALDH1A1 | |
| SCHEMBL2847041 | 0.77 | TP53 (0.55) | TP53LMNAMAPT | |
| SCHEMBL2841679 | 0.77 | ALDH1A1 (0.56) | TP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | claimed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |