SCHEMBL13382016

SCHEMBL13382016

FC(F)(F)c1ccc(-c2ccc(-c3ccc(C(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.68
ACP3 P15309 1/20 0.53
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
BACE1 P56817 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.47
SLC6A2 P23975 3/20 0.45
SLC6A4 P31645 3/20 0.45
SLC6A3 Q01959 3/20 0.45
CASR P41180 2/20 0.44
FFAR1 O14842 3/20 0.43
HSD11B1 P28845 1/20 0.42
KCNK2 O95069 1/20 0.42
KCNH2 Q12809 1/20 0.42
CACNA1C Q13936 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2493440 0.84 CES2 (0.48) KIF11ACP3ALDH1A1TSHR
SCHEMBL11540603 0.84 SLC6A3 (0.69) KIF11ACP3ALDH1A1TSHRPTGDR2
SCHEMBL2271905 0.84 KIF11 (0.63) KIF11ACP3ALDH1A1TSHRBACE1
SCHEMBL2271902 0.84 KIF11 (0.63) KIF11ACP3ALDH1A1TSHRBACE1
SCHEMBL2271910 0.84 KIF11 (0.63) KIF11ACP3ALDH1A1TSHRBACE1
SCHEMBL163728 0.82 KIF11 (1.00) KIF11ALDH1A1TSHRBACE1KCNH2
SCHEMBL9306866 0.82 SLC6A2 (0.55) ACP3ALDH1A1TSHRSLC6A2SLC6A4
Ammonia Solution, Strong SCHEMBL21809401 0.80 KIF11 (0.95) KIF11ALDH1A1TSHRBACE1KCNH2
SCHEMBL27887943 0.80 KIF11 (0.95) KIF11ALDH1A1TSHRBACE1KCNH2
Water SCHEMBL7382449 0.80 KIF11 (0.95) KIF11ALDH1A1TSHRBACE1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010040438-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2010-04-15 WO disclosed