Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980210 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL982824 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL983250 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL982044 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL982532 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL984576 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL983446 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL134426 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL982845 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A | |
| SCHEMBL352666 | 1.00 | THRB (0.42) | THRBTSHRMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200197500-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | SEATTLE PROJECT CORP. | 2020-06-25 | — | — | US | claimed |
| CN-108025091-A | Solid lipid magnetic resonance nano particle and its preparation method and application | 浙江大学 | 2018-05-11 | — | — | CN | claimed |
| CN-105530952-A | Compositions and vaccines for treating lung cancer | CUREVAC GMBH | 2016-04-27 | — | — | CN | claimed |
| CN-105517566-A | Compositions and vaccines for treating prostate cancer | CUREVAC GMBH | 2016-04-20 | — | — | CN | claimed |
| US-8222257-B2 | Phosphono-pent-2-en-1-yl nucleosides and analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-17 | — | — | US | claimed |
| US-20090215726-A1 | Phosphono-Pent-2-en-1-yl Nucleosides and Analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-27 | — | — | US | claimed |
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-18 | — | — | US | claimed |
| EP-1866319-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006137953-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA (US) | 2006-12-28 | — | — | WO | claimed |
| WO-2006130217-A2 | SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-07 | — | — | WO | claimed |
| US-5338642-A | Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | claimed |
| US-4701284-A | ANIONIC SURFACTANTS, WATER SOLUBILITY, LOW-VISCOSITY LATEX BY EMULSION POLYMERIZATION, ANTIFOAM AGENTS; ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-20 | — | — | US | claimed |
| US-4004927-A | Photographic light-sensitive material containing liquid organopolysiloxane | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-25 | — | — | US | claimed |
| US-20240197636-A1 | TISSUE-SPECIFIC NUCLEIC ACID DELIVERY BY MIXED CATIONIC LIPID PARTICLES | OMEGA THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | US | disclosed |
| US-20240115730-A1 | TISSUE-SPECIFIC NUCLEIC ACID DELIVERY BY 1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE (DOTAP) LIPID NANOPARTICLES | OMEGA THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| WO-2024073678-A2 | PHOSPHOLIPIDS CONTAINING A HETEROCYCLE RING HAVING A TERTIARY AMINE OR AMIDE | OMEGA THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| EP-0020297-A1 | Cyclic phosphoric acid ester amides, process for their preparation and their use as stabilizers | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |
| EP-0005441-A1 | Aminodibenzoxaphosphorines, process for their preparation and their use as stabilisators | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |
| EP-0005500-A1 | Dioxaphosphepines, their preparation and use as stabilisers for organic materials | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |
| US-4004927-A | Photographic light-sensitive material containing liquid organopolysiloxane | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | PNP, TYMP, ENPP1 | THRB 2027/4885TSHR 3232/4885MEN1 2049/4885 |
| US-20090215726-A1 | Phosphono-Pent-2-en-1-yl Nucleosides and Analogs | PNP, TYMP, ENPP1 | THRB 2233/4885TSHR 3345/4885MEN1 1848/4885 |
| US-20200197500-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | TSG101, TP53, MICA | THRB 4395/4885TSHR 4836/4885MEN1 3233/4885 |
| US-20240197636-A1 | TISSUE-SPECIFIC NUCLEIC ACID DELIVERY BY MIXED CATIONIC LIPID PARTICLES | LIPC, FABP1, RNASE1 | THRB 2202/4885TSHR 1166/4885MEN1 2230/4885 |
| US-20240115730-A1 | TISSUE-SPECIFIC NUCLEIC ACID DELIVERY BY 1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE (DOTAP) LIPID NANOPARTICLES | LPAR2, LPAR1, PHOSPHO1 | THRB 1557/4885TSHR 892/4885MEN1 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.