Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262280 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL134427 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL981208 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL984577 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL625344 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983251 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL982046 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL352667 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL982846 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983447 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200197500-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | SEATTLE PROJECT CORP. | 2020-06-25 | — | — | US | claimed |
| CN-108025091-A | Solid lipid magnetic resonance nano particle and its preparation method and application | 浙江大学 | 2018-05-11 | — | — | CN | claimed |
| CN-105530952-A | Compositions and vaccines for treating lung cancer | CUREVAC GMBH | 2016-04-27 | — | — | CN | claimed |
| CN-105517566-A | Compositions and vaccines for treating prostate cancer | CUREVAC GMBH | 2016-04-20 | — | — | CN | claimed |
| US-8222257-B2 | Phosphono-pent-2-en-1-yl nucleosides and analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-07-17 | — | — | US | claimed |
| WO-2009129387-A2 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | claimed |
| WO-2009129385-A1 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | claimed |
| US-20090215726-A1 | Phosphono-Pent-2-en-1-yl Nucleosides and Analogs | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-08-27 | — | — | US | claimed |
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-18 | — | — | US | claimed |
| EP-1866319-A1 | PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006130217-A2 | SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-07 | — | — | WO | claimed |
| EP-0463485-B1 | Process for the production of flexographic relief printing plates | BASF AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0316618-B1 | Multilayer flat light sensitive registration material | BASF AG (DE) | 1994-08-17 | — | — | EP | claimed |
| US-5338642-A | Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-16 | — | — | US | claimed |
| US-5035981-A | Having a top layer of high-strength, transparent, soluble or swellable polymer containing an antistatic agent of an ethoxylated amine or amide; exposure; development | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-30 | — | — | US | claimed |
| US-4946758-A | RELIEF IMAGE FORMING LAYER; HIGH TENSILE STRENGTH POLYMER AND COVERING | BASF AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | claimed |
| EP-0142467-B1 | POLYMER COMPOUNDS CONTAINING PIPERIDYL GROUPS AND THEIR USE AS STABILISERS IN SYNTHETIC POLYMERS | CIBA-GEIGY S.p.A. (IT) | 1988-08-24 | — | — | EP | claimed |
| US-4701284-A | ANIONIC SURFACTANTS, WATER SOLUBILITY, LOW-VISCOSITY LATEX BY EMULSION POLYMERIZATION, ANTIFOAM AGENTS; ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-20 | — | — | US | claimed |
| US-4294620-A | Phthalocyanine formulations | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | claimed |
| US-4004927-A | Photographic light-sensitive material containing liquid organopolysiloxane | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156545-A1 | Substituted Phosphate Esters of Nucleoside Phosphonates | PNP, TYMP, ENPP1 | THRB 2027/4885HTT 3456/4885MEN1 2049/4885 |
| US-20090215726-A1 | Phosphono-Pent-2-en-1-yl Nucleosides and Analogs | PNP, TYMP, ENPP1 | THRB 2233/4885HTT 2961/4885MEN1 1848/4885 |
| US-20200197500-A1 | ALPHAVIRUS NEOANTIGEN VECTORS | TSG101, TP53, MICA | THRB 4395/4885HTT 3407/4885MEN1 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.