Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262280 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL134427 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL981208 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL133830 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL984577 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL625344 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983251 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL982046 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL352667 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT | |
| SCHEMBL983447 | 1.00 | THRB (0.56) | THRBHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475832-B2 | Phosphonates with reduced toxicity for treatment of viral infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-25 | — | — | US | claimed |
| US-20150080344-A1 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION | 2015-03-19 | — | — | US | claimed |
| US-8846643-B2 | Phosphonates with reduced toxicity for treatment of viral infections | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-30 | — | — | US | claimed |
| EP-2558466-A2 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | The Regents of the University of California (US) | 2013-02-20 | — | — | EP | claimed |
| US-20130029940-A1 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-01-31 | — | — | US | claimed |
| WO-2011130557-A2 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-10-20 | — | — | WO | claimed |
| CN-118302407-A | Carbonyl compound, method for producing isocyanate compound, and isocyanate composition | 旭化成株式会社 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |
| WO-2023080258-A1 | CARBONYL COMPOUND, METHOD FOR PRODUCING CARBONYL COMPOUND, METHOD FOR PRODUCING ISOCYANATE COMPOUND, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| EP-2088138-B1 | Process for producing isocyanate | ASAHI KASEI CHEMICALS CORP (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-8362293-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-0090285-A2 | Pigment preparations and their use in pigmenting heliographic and lac colours | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |
| EP-0014962-B1 | PREPARATIONS OF PHTHALOCYANINES AND OFFSET PRINTING DYES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1982-09-22 | — | — | EP | disclosed |
| EP-0014907-B1 | PIGMENT PREPARATIONS AND LAKES OR PRINTING DYES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4294620-A | Phthalocyanine formulations | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4255203-A | COMPRISING AN ORGANIC PIGMENT AND AN ARYL BISUREA DERIVATIVE; PRINTING INKS; PAINTS; GLOSS; COLOR INTENSITY, AND FLUID FLOW | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |
| EP-0014907-A1 | Pigment preparations and lakes or printing dyes containing them | BASF Aktiengesellschaft (DE) | 1980-09-03 | — | — | EP | disclosed |
| EP-0014962-A1 | Preparations of phthalocyanines and offset printing dyes containing them | BASF Aktiengesellschaft (DE) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029940-A1 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | POLRMT, PNP, MTAP | THRB 1729/4885HTT 1612/4885MEN1 4546/4885 |
| US-20150080344-A1 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | POLRMT, PNP, MTAP | THRB 1729/4885HTT 1612/4885MEN1 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.