SCHEMBL625344

SCHEMBL625344

[CH2]CCOCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.56
HTT P42858 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MAPT P10636 1/20 0.56
CES2 O00748 2/20 0.46
TSHR P16473 4/20 0.44
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
USP2 O75604 1/20 0.43
CES1 P23141 1/20 0.42
SPHK1 Q9NYA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262280 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL134427 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL981208 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL133830 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL984577 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL983251 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL982046 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL352667 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL982846 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL983447 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161596-A1 NANOFIBROUS MATERIAL PARTICULARLY FOR TOPICAL USE IN THERAPIES Univerzita Karlova (CZ) 2023-04-12 EP claimed
US-11135237-B2 Lipophosphonoxins of second generation, and their use USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2021-10-05 US claimed
US-20210220383-A1 LIPOPHOSPHONOXINS OF SECOND GENERATION, AND THEIR USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2021-07-22 US claimed
EP-3448865-B1 LIPOPHOSPHONOXINS OF SECOND GENERATION, AND THEIR USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2019-09-04 EP claimed
WO-2017186200-A1 LIPOPHOSPHONOXINS OF SECOND GENERATION, AND THEIR USE USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2017-11-02 WO claimed
EP-2527351-B1 Lipophosphonoxins, method of their preparation and use USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2013-12-11 EP claimed
WO-2012021472-A2 COMPOSITIONS AND METHODS FOR SEALING THE SURFACE OF KERATINOUS SUBSTRATES L'OREAL S. A. (FR) 2012-02-16 WO claimed
US-20050076578-A1 Tunable composition and method for chemical-mechanical planarization with aspartic acid/tolyltriazole VERSUM MATERIALS US, LLC 2005-04-14 US claimed
JP-3602057-B2 2004-12-15 JP claimed
JP-2002538287-A 2002-11-12 JP claimed
EP-1124920-A1 CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, Inc. (US) 2001-08-22 EP claimed
WO-2000053703-A1 CYCLIC THIOUREA ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2000-09-14 WO claimed
EP-0316618-B1 Multilayer flat light sensitive registration material BASF AG (DE) 1994-08-17 EP claimed
US-5275749-A Lubricants with corrosion inhibitors KING INDUSTRIES, INC. (US) 1994-01-04 US claimed
US-4294620-A Phthalocyanine formulations BASF AKTIENGESELLSCHAFT (DE) 1981-10-13 US claimed
CN-118302407-A Carbonyl compound, method for producing isocyanate compound, and isocyanate composition 旭化成株式会社 2024-07-05 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
US-4255203-A COMPRISING AN ORGANIC PIGMENT AND AN ARYL BISUREA DERIVATIVE; PRINTING INKS; PAINTS; GLOSS; COLOR INTENSITY, AND FLUID FLOW BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed
EP-0014907-A1 Pigment preparations and lakes or printing dyes containing them BASF Aktiengesellschaft (DE) 1980-09-03 EP disclosed
EP-0014962-A1 Preparations of phthalocyanines and offset printing dyes containing them BASF Aktiengesellschaft (DE) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11135237-B2 Lipophosphonoxins of second generation, and their use PLA2G1B, PLA2G2E, PLA2G4C THRB 2528/4885HTT 4124/4885MEN1 1905/4885
US-20210220383-A1 LIPOPHOSPHONOXINS OF SECOND GENERATION, AND THEIR USE PLA2G1B, PLA2G2E, PLA2G4C THRB 2528/4885HTT 4124/4885MEN1 1905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.