Sugi Predict

Sugi Predict / Compounds / SCHEMBL134427

SCHEMBL134427

SCHEMBL134427

[CH2]CCOCCCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.56
▸ HTT P42858 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ KMT2A Q03164 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ CES2 O00748 2/20 0.46
▸ TSHR P16473 4/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ CES1 P23141 1/20 0.42
▸ SPHK1 Q9NYA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262280 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL981208 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL133830 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL984577 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL625344 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL983251 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL982046 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL352667 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL982846 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT
SCHEMBL983447 1.00 THRB (0.56) THRBHTTMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 526 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS EMORY UNIVERSITY 2024-05-30 — — US claimed
CN-117881402-A Nucleotide and nucleoside therapeutic compositions, combinations, and uses related thereto 埃默里大学 2024-04-12 — — CN claimed
EP-4333859-A1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS, COMBINATIONS AND USES RELATED THERETO Emory University (US) 2024-03-13 — — EP claimed
WO-2023152709-A1 RNA POLYMERASE INHIBITORS AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-17 — — WO claimed
EP-4161596-A1 NANOFIBROUS MATERIAL PARTICULARLY FOR TOPICAL USE IN THERAPIES Univerzita Karlova (CZ) 2023-04-12 — — EP claimed
CN-113332305-B Lipid composition of cytidine compound 中国医学科学院医药生物技术研究所 2022-08-16 — — CN claimed
CN-113336816-B Cytidine compounds and anti-tumor application thereof 中国医学科学院医药生物技术研究所 2022-05-17 — — CN claimed
CN-114249788-A Non-natural base nucleotide phosphate monoester prodrug molecule and preparation method and application thereof 河南师范大学 2022-03-29 — — CN claimed
CN-112266400-B Antitumor compounds 中国医学科学院医药生物技术研究所 2022-02-22 — — CN claimed
US-11135237-B2 Lipophosphonoxins of second generation, and their use USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2021-10-05 — — US claimed
WO-2010146127-A1 PHOSPHONATES SYNTHONS FOR THE SYNTHESIS OF PHOSPHONATES DERIVATIVES SHOWING BETTER BIOAVAILABILITY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-12-23 — — WO claimed
WO-2009129387-A2 CATIONIC LIPIDS AND USES THEREOF ABBOTT LABORATORIES (US) 2009-10-22 — — WO claimed
US-20090215726-A1 Phosphono-Pent-2-en-1-yl Nucleosides and Analogs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-08-27 — — US claimed
US-20090156545-A1 Substituted Phosphate Esters of Nucleoside Phosphonates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-06-18 — — US claimed
EP-1866319-A1 PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-12-19 — — EP claimed
WO-2006137953-A1 PHOSPHONO-PENT-2-EN-1-YL NUCLEOSIDES AND ANALOGS THE REGENTS OF THE UNIVERISITY OF CALIFORNIA (US) 2006-12-28 — — WO claimed
WO-2006130217-A2 SUBSTITUTED PHOSPHATE ESTERS OF NUCLEOSIDE PHOSPHONATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-12-07 — — WO claimed
WO-2006076015-A2 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-07-20 — — WO claimed
EP-0316618-B1 Multilayer flat light sensitive registration material BASF AG (DE) 1994-08-17 — — EP claimed
US-4294620-A Phthalocyanine formulations BASF AKTIENGESELLSCHAFT (DE) 1981-10-13 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156545-A1 Substituted Phosphate Esters of Nucleoside Phosphonates PNP, TYMP, ENPP1 THRB 2027/4885HTT 3456/4885MEN1 2049/4885
US-20090215726-A1 Phosphono-Pent-2-en-1-yl Nucleosides and Analogs PNP, TYMP, ENPP1 THRB 2233/4885HTT 2961/4885MEN1 1848/4885
US-11135237-B2 Lipophosphonoxins of second generation, and their use PLA2G1B, PLA2G2E, PLA2G4C THRB 2528/4885HTT 4124/4885MEN1 1905/4885
US-20240173345-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING SUBSTITUTED NUCLEOTIDE AND NUCLEOSIDE FOR TREATING VIRAL INFECTIONS PNP, NTPCR, TYMP THRB 3281/4885HTT 1111/4885MEN1 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.