Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383635 | 0.96 | LTA4H (0.50) | LTA4HCHRNB4CHRNA3POLB | |
| SCHEMBL13383606 | 0.89 | LTA4H (0.52) | LTA4HCHRNB4CHRNA3POLB | |
| SCHEMBL12266408 | 0.88 | LTA4H (0.49) | LTA4HCHRNB4CHRNA3POLBCHRNB2 | |
| SCHEMBL12266413 | 0.85 | LTA4H (0.50) | LTA4HCHRNB4CHRNA3POLB | |
| SCHEMBL13383566 | 0.81 | LTA4H (0.48) | LTA4HCHRNB4CHRNA3 | |
| SCHEMBL12266393 | 0.79 | LTA4H (0.52) | LTA4HCHRNB4CHRNA3POLBCHRNB2 | |
| SCHEMBL12266365 | 0.79 | LTA4H (0.48) | LTA4HCHRNB4CHRNA3POLBCHRNB2 | |
| SCHEMBL12270172 | 0.78 | LTA4H (0.43) | LTA4HCHRNB4CHRNA3 | |
| SCHEMBL18586392 | 0.75 | CHRNB4 (0.71) | LTA4HCHRNB4CHRNA3 | |
| SCHEMBL13383650 | 0.69 | ENPP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | KCNMB4, CA2, NR0B2 | LTA4H 4660/4885CHRNB4 79/4885CHRNA3 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.